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JCL Roundtable: European perspective on comprehensive lipid management and cardiovascular health
Triglycerides and Remnant Cholesterol Need More Focus:The discussion highlighted the need for more potent therapies target...
Meta-analysis: Lipids, Vascular Function, Cardio-Cerebrovascular Events after Previous Kawasaki Disease in Children
Kawasaki disease (KD) is an acute multisystem vasculitis that is the leading cause of acquired heart disease in children i...
SEX DIFFERENCES IN INFLAMMATORY BIOMARKERS DURING LONG-TERM EVOLOCUMAB THERAPY
Introduction and objectivesAtherosclerotic cardiovascular disease remains a predominant cause of morbidity and mortality w...
From Clinical Inertia to Therapeutic Optimization in Patients with Atherosclerotic Cardiovascular Disease: A Monte Carlo Simulation within the ITACARE-P Registry
Low-density lipoprotein cholesterol (LDL-C) is a well-established, modifiable causal factor in atherosclerotic cardiovascu...
Liver Diseases and Low Serum Albumin as Potential Confounders in the Association Between Low Total Cholesterol and Elevated All-cause and Cancer Mortality: The Japan Multi-Institutional Collaborative Cohort (J-MICC) Study
The benefit of cholesterol-lowering for the prevention of atherosclerotic cardiovascular disease has been extensively show...
DHCR24-Related Desmosterolosis in the First Reported Turkish Patient: Expanding the Genotypic and Phenotypic Spectrum
Desmosterolosis (OMIM #602398) is a ultra-rare autosomal recessive disorder characterized by multiple congenital anomalies...
ApoB/LDL-C Discordance as a Predictor of Atherosclerotic Cardiovascular Disease in Genetically Confirmed Heterozygous Familial Hypercholesterolemia: A Hypothesis-Generating Cohort Study
Available online 16 November 2025Author links open overlay panel, ABSTRACTBackgroundIn heterozygous familial hypercholeste...
Efficacy and Safety of Ongericimab in Patients with Dyslipidemia: A Grade-Assessed Systematic Review and Meta-analysis of Randomized Controlled Trials
Hypercholesterolemia is clinically defined by the 2018 American College of Cardiology/American Heart Association (ACC/AHA)...
Metabolic and Functional Aspects of High-Density Lipoproteins (HDL) in Familial Hypercholesterolemia with or without Subclinical Coronary Atherosclerosis
Familial hypercholesterolemia (FH) is the most common monogenic disease (1), with more than 90% of affected individuals ca...
Response to letter to the editor by Matsubara and colleagues
Available online 27 November 2025Author links open overlay panel, , , Section snippetsUse of AI and AI-assisted technologi...
Kawasaki disease and familial hypercholesterolemia: Their potential synergistical impact on coronary arterial vascular health and viewpoints
Available online 27 November 2025Author links open overlay panel, , Section snippetsDeclaration of generative AI and AI-as...
Elevated lipoprotein(a) in patients with premature atherosclerotic cardiovascular disease: insights from a large US real-world cohort
Patients experiencing premature cardiovascular events (males: <55 years; females: <65 years) represent a high-risk s...
Improvement of severe hypertriglyceridaemia in atypical subtype 4 partial lipodystrophy with volanesorsen
Lipodystrophy is a rare metabolic disorder resulting from adipose tissue abnormalities. Lipodystrophy can be divided by ae...
Sequencing and Functional Characterization of SCARB1 Variants in subjects with Extreme HDL cholesterol levels
Available online 1 December 2025Author links open overlay panel, , , , , , , , Highlights•SCARB1 was sequenced in 96 extre...
Lipoprotein(a) at the Crossroads of Inflammation and Atherosclerosis in Rheumatoid Arthritis: A Narrative Review
Rheumatoid arthritis (RA; Table 1) is a chronic systemic autoimmune disorder primarily affecting synovial joints, characte...
Lipid-lowering Therapies to Target Cardiac Allograft Vasculopathy After Heart Transplantation: Current Evidence and Future Directions
Taha Mansoor: Writing – review & editing, Writing – original draft, Visualization, Validation, Supervision, Software, ...
Examining Barriers and Facilitators to Testing Lipoprotein (a): Understanding At-Risk Individual and Clinician Perspectives
Objective: Lipoprotein(a), or Lp(a), is a significant risk factor for cardiovascular disease, yet is infrequently measured...
Severe Hypercholesterolemia in a Pediatric Cohort: Familial Homozygous and Autosomal Recessive Hypercholesterolemia
Familial hypercholesterolemia (FH) arises from variants in genes critical to the receptor-mediated removal of low-density ...
Myocardial infarction risk and the clinical significance of metabolic syndrome in the absence of hypertension and diabetes: Insights from a large cohort screening population
Myocardial infarction (MI) continues to be a major cause of mortality, contributing to the burden on individuals and socie...
Gender Differences in Lipid Management, LDL-C Goal Attainment, and Prescribing Practices
Cardiovascular disease (CVD) is the leading cause of death in men and women worldwide. Meta-analyses of the Cholesterol Tr...
Developing a national implementation strategy for enhancing the detection of familial hypercholesterolemia: An Australian experience
Available online 20 March 2025Author links open overlay panel, , , , , , , , , , , , , , , , , , , Highlights•Developed a ...
Hourly 4-minute walking breaks from sitting following aerobic exercise reduce postprandial non-HDL cholesterol in healthy young adults - A randomized crossover trial
Young adults often engage in high amounts of sedentary behavior (SB),1 which is defined as “any waking behavior characteri...
Association between remnant cholesterol and culprit vessel physiological features in patients with acute coronary syndrome: An optical coherence tomography study
Acute coronary syndrome (ACS) is a clinical syndrome caused by the rupture of coronary atherosclerotic plaques, leading to...
Prevention of Acute Systemic Reaction During LDL apheresis post COVID-19 by Icatibant Pre-Treatment
Familial hypercholesteremia (FH) is a genetic disorder that is due to LDLR, APOB, and PCSK9 gene mutations resulting in ve...
Low-density lipoprotein cholesterol elevation, ketogenic diets, body mass index, and heterozygous ABCG5 genetic variation: Review, case report, and large population analysis
Available online 21 March 2025Author links open overlay panel, , , , , , Highlights•A lean 51-year-old female had an LDL-C...
IS TANGIER DISEASE A RARE CAUSE OF PREMATURE OVARIAN INSUFFICIENCY? – A CASE REPORT
Tangier disease (TD) is a rare inherited disorder of lipoprotein metabolism, characterised by the accumulation of choleste...
Familial chylomicronemia syndrome: An expert clinical review from the National Lipid Association
Familial chylomicronemia syndrome (FCS) is a rare Mendelian autosomal recessive disorder (MIM 238600) characterized by ext...
Triglyceride-rich lipoprotein sphingolipids are altered in primary hypertension: A pilot case-control study
Available online 26 March 2025Author links open overlay panel, , , , , , , , , , , Highlights•Patients with primary hypert...
Epidemiology and longitudinal course of chylomicronemia: Insights from NHANES and a large health care system
BACKGROUNDChylomicronemia is characterized by fasting triglyceride (TG) ≥1000 mg/dL; its longitudinal course is not well s...
Recognition and Management of Persistent Chylomicronemia: A Joint Expert Clinical Consensus by the National Lipid Association and the American Society for Preventive Cardiology
Extreme hypertriglyceridemia, defined as triglyceride (TG) levels ≥1000 mg/dL, is almost always indicative of chylomicrone...
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