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Active surveillance and risk prediction of piperacillin/tazobactam‑associated hypokalaemia: development and external validation of a clinical nomogram
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Biosimilar use in medical oncology in Ireland: a missed opportunity to mitigate financial toxicity?
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Cost-effectiveness of first-line pembrolizumab monotherapy in PD-L1–high metastatic non-small cell lung cancer in Australia: evidence from trials and real-world practice
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Effectiveness of continuous pharmacist intervention at maintaining dose intensity in postoperative adjuvant S-1 chemotherapy for gastric cancer: a multicentre retrospective study
Maintaining dose intensity is essential for ensuring the efficacy of adjuvant S-1 chemotherapy in gastric cancer. Although...
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Development and validation of a PD-L1 and tumor mutational burden-based predictive model for pathological complete response after neoadjuvant immunotherapy in resectable lung cancer
Neoadjuvant immunotherapy has demonstrated promising efficacy in resectable lung cancer; however, substantial interindivid...
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Global burden and future trends of type 2 diabetes mellitus-associated chronic kidney disease: analysis of the Global Burden of Disease Study 2021
Type 2 diabetes mellitus-associated chronic kidney disease (T2DM-associated CKD) is a major cause of kidney failure, cardi...
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Grounding clinical supervision in advanced pharmacy practice: a new conceptual model
Clinical supervision is a critical enabler of advanced pharmacist practice. Despite this, within the United Kingdom, it re...
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Prioritising medication management criteria to identify emergency department patients with potential medication-related harm: Nominal Group Technique workshops with clinicians
Pharmacist involvement in the emergency department (ED) and early in a patient’s hospital stay improves clinical out...
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Comparative clinical evaluation of endothelin receptor antagonists in pulmonary arterial hypertension using a multi-criteria decision analysis framework
Endothelin receptor antagonists are important therapies for pulmonary arterial hypertension, but differences in efficacy, ...
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Developing pharmacist practice through a pilot family practice preceptorship programme: a prospective quantitative pre–post evaluation
Primary care health services face workforce pressures internationally. Greater multidisciplinary working is seen as a solu...
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Effects of antidepressant administration on physical performance and perceived exertion in athletes: systematic review and meta-analysis
Antidepressants are commonly prescribed in athletes with depressive disorders, yet their potential effects on physical per...
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AI-generated patient information leaflets for oral anticoagulants: quality, usability, readability, and reproducibility compared with FDA-referenced materials
Oral anticoagulants are frequently associated with preventable hospital admissions, and patient education is essential to ...
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Medicine shortages and glaucoma care: a time-series analysis indicating population-level consequences of a national timolol eye drop shortage
Medicine shortages can disrupt glaucoma management and necessitate therapeutic substitution. Understanding how shortages a...
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Codesigning a pharmacist-led transition of care program in the emergency department: a qualitative participatory study
Transitions from the emergency department (ED) to home are high-risk periods for medication-related harm. Pharmacist-led i...
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Instruments for assessing healthcare professionals’ knowledge, attitudes and practices regarding deprescribing: a scoping review
Deprescribing is a multiprofessional process which aims to optimize medication use and improve patient safety, in which he...
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Development of a hybrid artificial intelligence framework for pharmacotherapy optimization
Pharmacotherapy optimization in multimorbid patients is increasingly complex due to polypharmacy, fragmented data, expandi...
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Development and internal validation of an interpretable machine learning model for predicting vancomycin-induced nephrotoxicity in hospitalized children
Vancomycin is widely used for severe Gram‑positive infections in children, but vancomycin‑induced nephrotoxici...
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Developing a core competency framework for psychiatric pharmacists: a Europe-wide e-Delphi consensus study conducted by the European Society of Clinical Pharmacy Mental Health Special Interest Group
Consensus on essential clinical activities of psychiatric pharmacists is currently unavailable. Agreement on core non-clin...
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Pharmacist input to depression screening and management in patients with diabetes: a systematic review
Depression affects approximately 5% of the global adult population, and its clinical and economic burden is particularly p...
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Multilevel determinants of medication adherence among Chinese patients with chronic diseases: an ecological analysis based on the health ecology model
Medication adherence is essential for the effective management of chronic diseases; however, adherence among patients rema...
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Severe cutaneous adverse reactions linked to medications in children and adolescents: a pharmacovigilance study based on the FDA Adverse Event Reporting System database
Severe cutaneous adverse reactions (SCARs) are rare but potentially life-threatening. Children and adolescents are especia...
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Characteristics and outcomes of pharmacy-supported transitions of care interventions in emergency departments: a scoping review
Transitions of care (ToC) services are essential for maintaining care continuity. The complex and fast-paced nature of car...
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Adherence to biologics in patients with inflammatory bowel disease: a systematic review and meta-analysis
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Exploring pharmacist prescribing practices in general practices for atrial fibrillation in England: a qualitative study using the theoretical domains framework
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Long-term safety, effectiveness, and cost of rapamycin- vs. everolimus-eluting stents in acute coronary syndrome: a real-world cohort study
Drug-eluting stents are the cornerstone of treatment in patients with Acute Coronary Syndrome (ACS) undergoing Percutaneou...
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Targeting pyroptosis in atherosclerosis: emerging pharmacologic strategies and natural compound-based therapeutics—a narrative review
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Risk factor analysis of hypertonic saline non-responders for the treatment of cerebral edema: a retrospective cohort study
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Beyond existing rating scales: development of a novel nomogram for predicting severe clinical bleeding associated with low-molecular-weight heparin in hospitalized medical patients
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Sodium-glucose cotransporter-2 inhibitors and risk of diabetic retinopathy in type 2 diabetes: a network meta-analysis of randomised clinical trials
Sodium–glucose cotransporter‑2 (SGLT‑2) inhibitors are widely used in type 2 diabetes, but their effect ...
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Impact of an AI-powered hospital admission prediction dashboard to guide medication reconciliation in the emergency department: a retrospective before-after study
Medication reconciliation (MR) in the emergency department (ED) is essential to ensure medication safety, especially for p...
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