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The spectrum of congestion in heart failure: underlying pathophysiology and diagnostic strategies
The spectrum of congestion in heart failure: underlying pathophysiology and diagnostic strategies
Congestion is the main driver of heart failure (HF) recurrence and its relief remains the primary therapeutic target durin...
Mineralocorticoid receptor antagonists for the treatment of heart failure and kidney disease: a state-of-the-art review
Mineralocorticoid receptor antagonists for the treatment of heart failure and kidney disease: a state-of-the-art review
Chronic heart failure causes significant morbidity and mortality worldwide. Mineralocorticoid receptor antagonists are piv...
State-of-the-art management of ischemic cardiomyopathy: integrating diagnostic pathways, revascularization strategies, and guideline-directed therapy
State-of-the-art management of ischemic cardiomyopathy: integrating diagnostic pathways, revascularization strategies, and guideline-directed therapy
Ischemic cardiomyopathy (ICM) is a major cause of cardiovascular morbidity and mortality, characterized by a complex patho...
Association between SGLT2 inhibitors and outcomes after heart transplant in patients with type 2 diabetes: A systematic review and meta-analysis
Association between SGLT2 inhibitors and outcomes after heart transplant in patients with type 2 diabetes: A systematic review and meta-analysis
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are recommended for multiple populations—type 2 diabetes (T2D), c...
Cardiac microcurrent therapy in heart failure: Mechanistic rationale, early clinical evidence, and future directions
Cardiac microcurrent therapy in heart failure: Mechanistic rationale, early clinical evidence, and future directions
Despite major advances in guideline-directed medical therapy (GDMT), many patients with heart failure with reduced ejectio...
Left ventricular non-compaction in heart failure: contemporary perspective on diagnostic challenges and treatment opportunities
Left ventricular non-compaction in heart failure: contemporary perspective on diagnostic challenges and treatment opportunities
Left ventricular non-compaction (LVNC) remains one of the most debated phenotypes within the spectrum of cardiomyopathy. I...
Beyond the right ventricle: left heart involvement in pulmonary arterial hypertension
Beyond the right ventricle: left heart involvement in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is characterized by progressive remodeling of the pulmonary vasculature, leading to ...
Beyond vasodilation: sotatercept and the remodeling hypothesis in hfpef-associated pulmonary hypertension
Beyond vasodilation: sotatercept and the remodeling hypothesis in hfpef-associated pulmonary hypertension
Pulmonary hypertension complicating heart failure with preserved ejection fraction (HFpEF), particularly the combined post...
Overcoming barriers to early diagnosis and treatment of p.Val142Ile amyloid transthyretin (ATTR) cardiomyopathy
Overcoming barriers to early diagnosis and treatment of p.Val142Ile amyloid transthyretin (ATTR) cardiomyopathy
The most common hereditary transthyretin (ATTRv) amyloidosis variant in the United States, Val122Ile (p.Val142Ile), is pre...
Mavacamten in adolescent obstructive hypertrophic cardiomyopathy: SCOUTing a way forward
Mavacamten in adolescent obstructive hypertrophic cardiomyopathy: SCOUTing a way forward
Paediatric obstructive hypertrophic cardiomyopathy (oHCM) is a rare inherited cardiac disease that may present from childh...
Tachycardia-induced cardiomyopathy: evolution of the concept and contemporary insights
Tachycardia-induced cardiomyopathy: evolution of the concept and contemporary insights
Tachycardia-induced cardiomyopathy (TIC) is a reversible form of myocardial dysfunction caused by sustained or recurrent t...
Left ventricular excessive trabeculation: pathophysiology, diagnostic challenges, and prognostic significance
Left ventricular excessive trabeculation: pathophysiology, diagnostic challenges, and prognostic significance
Excessive trabeculation has been considered the morphological hallmark of left ventricular non-compaction (LVNC), traditio...
Cardiomyopathy in glycogen storage diseases: diagnosis, prognosis, and advanced management
Cardiomyopathy in glycogen storage diseases: diagnosis, prognosis, and advanced management
Glycogen storage diseases (GSDs) are a heterogeneous group of rare and often under-recognized causes of inherited cardiomy...
Post-viral myocarditis
Post-viral myocarditis
Myocarditis is an inflammatory disease of the myocardium characterized by complex histological, immunological and molecula...
Ironing Out the Details: Advancing Diagnosis and Treatment of Iron Deficiency in Patients with Heart Failure with Preserved Ejection Fraction – A Narrative Review
Ironing Out the Details: Advancing Diagnosis and Treatment of Iron Deficiency in Patients with Heart Failure with Preserved Ejection Fraction – A Narrative Review
Iron deficiency (ID) is a highly prevalent and clinically significant comorbidity in heart failure with preserved ejection...
Beyond clinical congestion in acute heart failure: integrating lung ultrasound, venous doppler, and echocardiographic hemodynamics for imaging-guided decongestion
Beyond clinical congestion in acute heart failure: integrating lung ultrasound, venous doppler, and echocardiographic hemodynamics for imaging-guided decongestion
Acute heart failure (AHF) is a major cause of hospitalisation worldwide and remains associated with substantial early reho...
Fabry disease cardiomyopathy: Time for a closer heart rhythm monitoring?
Fabry disease cardiomyopathy: Time for a closer heart rhythm monitoring?
Cardiovascular disease represents the leading cause of death in patients with Anderson-Fabry disease (FD), with sudden car...
Evaluation of pulmonary hypertension in heart failure with preserved ejection fraction
Evaluation of pulmonary hypertension in heart failure with preserved ejection fraction
In contemporary clinical practice, pulmonary hypertension (PH) is most commonly caused by heart failure with preserved eje...
Cardiac rehabilitation in patients with heart failure: clinical recommendation based on a review of the evidence
Cardiac rehabilitation in patients with heart failure: clinical recommendation based on a review of the evidence
Cardiac rehabilitation (CR) is a comprehensive, multidisciplinary approach that combines exercise training, risk factor ma...
Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology
Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology
Lung ultrasonography (LUS) is a reliable and reproducible tool across various clinical settings. Its high diagnostic accur...
Heart failure and left ventricular ejection fraction: a necessary but imperfect partnership
Heart failure and left ventricular ejection fraction: a necessary but imperfect partnership
The left ventricular ejection fraction (LVEF) is the most commonly used index to assess left ventricular systolic function...
Diabetic cardiomyopathy: Mechanistic insights on molecular pathways and emerging therapeutic approaches
Diabetic cardiomyopathy: Mechanistic insights on molecular pathways and emerging therapeutic approaches
Diabetes and its complications represent a global burden to human health. Among diabetic microvascular and macrovascular c...
Phenotype-guided approach for device-based therapies in heart failure
Phenotype-guided approach for device-based therapies in heart failure
Device-based therapies have become integral in the management of heart failure (HF). By targeting structural or neurohormo...
Navigating heart failure: a plain-language summary to empower people with heart failure
Navigating heart failure: a plain-language summary to empower people with heart failure
Heart failure is a chronic condition that can result from multiple causes and occurs when the heart cannot pump enough blo...
Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated
Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated
Chronic obstructive pulmonary disease (COPD) and heart failure (HF) frequently coexist and interact through complex and bi...
The challenges of using electronic medical records (EMR) to facilitate guideline-directed medical therapy (GDMT) for patients with heart failure (HF) and chronic kidney disease (CKD)
The challenges of using electronic medical records (EMR) to facilitate guideline-directed medical therapy (GDMT) for patients with heart failure (HF) and chronic kidney disease (CKD)
Heart failure (HF) and chronic kidney disease (CKD) are prevalent comorbidities that significantly impact patient outcomes...
Special topics: heart failure–related cardiogenic shock, valvular heart disease and end-stage renal disease. Part 4 of the International Expert Opinion Series on Acute Heart Failure Management
Special topics: heart failure–related cardiogenic shock, valvular heart disease and end-stage renal disease. Part 4 of the International Expert Opinion Series on Acute Heart Failure Management
Acute heart failure (AHF) remains a major global health challenge, contributing significantly to morbidity, mortality, and...
Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists
Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists
Transthoracic echocardiography has a central role in the diagnosis and monitoring of cancer therapy-related cardiac dysfun...
Redefining endpoints in heart failure clinical trials: the emerging role of wearable technologies in contemporary trial design
Redefining endpoints in heart failure clinical trials: the emerging role of wearable technologies in contemporary trial design
Randomised controlled trials (RCTs) in heart failure (HF) have progressively broadened their primary endpoints over recent...
Management of arrhythmias in left ventricular assist device recipients
Management of arrhythmias in left ventricular assist device recipients
Left ventricular assist device (LVAD) implantation is an important surgical option for patients with advanced heart failur...
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