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Multi-Omics Association Analysis of Mitochondrial Genes in Hypertrophic Scars: Application of Mendelian Randomization
Multi-Omics Association Analysis of Mitochondrial Genes in Hypertrophic Scars: Application of Mendelian Randomization
Providing multi-omics insight into mitochondrial genes associated with Hypertrophic Scars (HS) through Mendelian randomiza...
Utility of Machine Learning to Characterize Gut Microbiota Dysbiosis and Its Clinical Implications in Inflammatory Bowel Disease
Utility of Machine Learning to Characterize Gut Microbiota Dysbiosis and Its Clinical Implications in Inflammatory Bowel Disease
ML and DL hold considerable promise for translating microbiome research into diagnostic and prognostic tools for IBD. Read...
Association of the Cumulative Inflammatory Index and Long-Term Mortality in Stroke-Associated Pneumonia
Association of the Cumulative Inflammatory Index and Long-Term Mortality in Stroke-Associated Pneumonia
The IIC can serve as a feasible and trustworthy biomarker for predicting mortality in SAP cases, enabling the detection of...
Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome
Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome
Examining whether fatigue and depressive symptoms in sarcoidosis remission relate to residual inflammation or oxidative st...
Preliminary Retrospective Analysis of X-Ray, CT, and MRI Imaging Features of Brucellar Spondylodiscitis Diagnosis
Preliminary Retrospective Analysis of X-Ray, CT, and MRI Imaging Features of Brucellar Spondylodiscitis Diagnosis
Exploring the X-ray, CT, and MRI imaging features of Brucellar spondylodiscitis (BS) across different stages and evaluate ...
Integration of Delta-Radiomics Features and Inflammatory Biomarkers for Neoadjuvant Chemo-Immunotherapy Efficacy in Locally Advanced Esophageal Squamous Cell Carcinoma
Integration of Delta-Radiomics Features and Inflammatory Biomarkers for Neoadjuvant Chemo-Immunotherapy Efficacy in Locally Advanced Esophageal Squamous Cell Carcinoma
Constructing a multi-omics model for predicting efficacy of NACI in LA-ESCC patients by integrating delta-radiomics featur...
Predictive Value of Traditional and Novel Composite Inflammatory Indicators for Severe and Refractory Mycoplasma pneumoniae Pneumonia in Children
Predictive Value of Traditional and Novel Composite Inflammatory Indicators for Severe and Refractory Mycoplasma pneumoniae Pneumonia in Children
Evaluating the predictive efficacy of single inflammatory indicators and novel composite inflammatory indicators for sever...
Platelet Indices and ApoA1 as Predictive Markers in Neoadjuvant Immunochemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Retrospective Study
Platelet Indices and ApoA1 as Predictive Markers in Neoadjuvant Immunochemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Retrospective Study
Baseline and preoperative blood parameters (MPV, PDW, P-LCR) and preoperative ApoA1 are valuable predictors of treatment r...
Elevated Serum HMGB1 Levels and Their Association with Stroke Risk of Paroxysmal Atrial Fibrillation
Elevated Serum HMGB1 Levels and Their Association with Stroke Risk of Paroxysmal Atrial Fibrillation
Investigating the association between serum HMGB1 levels and stroke through the long-term follow-up of patients with parox...
Single-Cell RNA Sequencing Reveals Microglial Heterogeneity and Functional States After Cerebral Ischemia-Reperfusion Injury
Single-Cell RNA Sequencing Reveals Microglial Heterogeneity and Functional States After Cerebral Ischemia-Reperfusion Injury
Analyzing the heterogeneity, activation trajectories, and metabolic states of microglia in ischemic stroke to identify the...
NCF2 as a Novel Diagnostic Biomarker in Ulcerative Colitis: Linking Macrophage Infiltration to Immune Dysregulation via Multi-Omics Analysis
NCF2 as a Novel Diagnostic Biomarker in Ulcerative Colitis: Linking Macrophage Infiltration to Immune Dysregulation via Multi-Omics Analysis
This study aims to comprehensively analyze NFC2's expression, its associated pathways, and its interplay with the immune m...
Association Between the Systemic Immune-Inflammation Index and 24-week Outcomes in Patients with HIV-Associated Cryptococcal Meningitis: Secondary Analysis of a Prospective Multicenter Cohort Study
Association Between the Systemic Immune-Inflammation Index and 24-week Outcomes in Patients with HIV-Associated Cryptococcal Meningitis: Secondary Analysis of a Prospective Multicenter Cohort Study
The association between SII levels before and during treatment, and 24-week outcomes in HCM patients, as well as its poten...
Huanglian Jiedu Decoction Alleviates Myocardial Ischemia-Reperfusion Injury via AKT-Mediated Regulation of Endoplasmic Reticulum Stress
Huanglian Jiedu Decoction Alleviates Myocardial Ischemia-Reperfusion Injury via AKT-Mediated Regulation of Endoplasmic Reticulum Stress
To investigate the role of AKT and ERS in the modulation of MIRI by Huanglian Jiedu Decoction (HLJDD) through in vitro and...
Integrated Multi-Omic Analysis Reveals Causal Relationships and Causal Mechanisms of Peripheral Lymphocyte-Driven Remodeling in the Intrahepatic Immune Microenvironment of Early-Stage MAFLD
Integrated Multi-Omic Analysis Reveals Causal Relationships and Causal Mechanisms of Peripheral Lymphocyte-Driven Remodeling in the Intrahepatic Immune Microenvironment of Early-Stage MAFLD
The causal relationships and underlying mechanisms between peripheral blood cell indices & intrahepatic immune microen...
Association of NLR and Ferritin in Osteoporotic Fractures Among Chinese Older Patients
Association of NLR and Ferritin in Osteoporotic Fractures Among Chinese Older Patients
Association of NLR and Ferritin in Osteoporotic Fractures Among Chinese Older Patients
Cuproptosis and Immune Microenvironment Interplay in Temporal Lobe Epilepsy: Identification of Key Molecular Signatures and Therapeutic Targets
Cuproptosis and Immune Microenvironment Interplay in Temporal Lobe Epilepsy: Identification of Key Molecular Signatures and Therapeutic Targets
Exploring cuproptosis in drug-resistant temporal lobe epilepsy: investigating copper-dependent cell death, targeting neuro...
Serum Cytokines as Predictive Biomarkers for Disease Severity in Pediatric Adenovirus Pneumonia
Serum Cytokines as Predictive Biomarkers for Disease Severity in Pediatric Adenovirus Pneumonia
Evaluating the clinical utility of serum cytokines as predictive biomarkers across severity-stratified pediatric adenoviru...
Comment on the Review: Clarifying Steroid-Associated Glaucoma—From Association to an Actionable Closed-Loop [Letter]
Comment on the Review: Clarifying Steroid-Associated Glaucoma—From Association to an Actionable Closed-Loop [Letter]
Letter for the article Safe Use of Corticosteroids in Non-Infectious Uveitis
MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis Expression
MCC950 Alleviates Experimental Autoimmune Neuritis by Inhibiting NLRP3 Inflammasome Activity and Down-Regulating Interleukin-23/Interleukin-17 Axis Expression
we used MCC950 a potent and highly selective NLRP3 inflammasome inhibitor to investigate the effect of NLRP3 inflammasome ...
Muscarinic Receptor-Mediated Electroacupuncture Modulation of Reactive Enteric Glial Cells Ameliorates Postoperative Ileus
Muscarinic Receptor-Mediated Electroacupuncture Modulation of Reactive Enteric Glial Cells Ameliorates Postoperative Ileus
To investigate the underlying mechanisms of electroacupuncture Zusanli acupoint (ST 36)-mediated functional restoration of...
Inflammation-Driven Prognosis in Advanced Heart Failure: A Machine Learning-Based Risk Prediction Model for One-Year Mortality
Inflammation-Driven Prognosis in Advanced Heart Failure: A Machine Learning-Based Risk Prediction Model for One-Year Mortality
This study aims to develop a ML-based prediction model focused on inflammation-driven prognosis in AdHF, with a particular...
Best Practices for Chronic Pancreatitis Pain Management: A Comprehensive Evidence-Based Review
Best Practices for Chronic Pancreatitis Pain Management: A Comprehensive Evidence-Based Review
Synthesizing the best available evidence on pain management in chronic pancreatitis through a systematic search, quality e...
Salmonella-NLRP3 Inflammasome Crosstalk: Host Defense Activation Versus Bacterial Immune Evasion Strategies
Salmonella-NLRP3 Inflammasome Crosstalk: Host Defense Activation Versus Bacterial Immune Evasion Strategies
In this study we explore the complex interplay of detection and evasion between NLRP3 inflammasome and Salmonella.
Comment on “Peripheral T Lymphocyte Predicts the Prognosis of Gastric Cancer Patients Undergoing Radical Gastrectomy: A Multicenter Retrospective Cohort Study” [Response to Letter]
Comment on “Peripheral T Lymphocyte Predicts the Prognosis of Gastric Cancer Patients Undergoing Radical Gastrectomy: A Multicenter Retrospective Cohort Study” [Response to Letter]
Response to Letter in regards to Comment on “Peripheral T Lymphocyte Predicts the Prognosis of Gastric Cancer Pa...
Development and Validation of Predictive Models for Inflammatory Bowel Disease Diagnosis: A Machine Learning and Nomogram-Based Approach
Development and Validation of Predictive Models for Inflammatory Bowel Disease Diagnosis: A Machine Learning and Nomogram-Based Approach
3 cohorts and developed risk prediction models for IBD, CD, and UC with good diagnostic capability, based on conventional ...
Mechanisms of Neuronal Differentiation and Notch Signaling as a Potential Therapeutic Target in Olfactory Dysfunction of Allergic Rhinitis
Mechanisms of Neuronal Differentiation and Notch Signaling as a Potential Therapeutic Target in Olfactory Dysfunction of Allergic Rhinitis
Mechanisms of Neuronal Differentiation and Notch Signaling as a Potential Therapeutic Target in Olfactory Dysfunction of A...
Mitochondrial Dysfunction and Reduced TCA Cycle Metabolite Levels in Inflammatory Bowel Disease Patients
Mitochondrial Dysfunction and Reduced TCA Cycle Metabolite Levels in Inflammatory Bowel Disease Patients
Reduced metabolites and respiratory complexes associated with the TCA indicate mitochondrial bioenergetic failure in IBD p...
Fatal Acute Intestinal Obstruction with Hemophagocytic Lymphohistiocytosis and Multiple Organ Failure in Adult-Onset Still’s Disease: A Rare Case Report
Fatal Acute Intestinal Obstruction with Hemophagocytic Lymphohistiocytosis and Multiple Organ Failure in Adult-Onset Still’s Disease: A Rare Case Report
We report the case of a 68-year-old man with adult-onset Still’s disease who developed acute intestinal obstruction,...
Exploring the Mechanism of Qinzhuliangxue Mixture for Treating Skin Lesions in Atopic Dermatitis: Insights from Network Pharmacology and Experimental Validation
Exploring the Mechanism of Qinzhuliangxue Mixture for Treating Skin Lesions in Atopic Dermatitis: Insights from Network Pharmacology and Experimental Validation
Atopic dermatitis (AD) is a chronic, recurrent inflammatory skin disorder that causes systemic skin lesions.
Longitudinal Changes in Peripheral and Alveolar Monocyte and Inflammatory Biomarkers are Distinct in Hypercapnia Patients Following Pulmonary Sepsis-Induced ARDS
Longitudinal Changes in Peripheral and Alveolar Monocyte and Inflammatory Biomarkers are Distinct in Hypercapnia Patients Following Pulmonary Sepsis-Induced ARDS
Our findings thus underscore the involvement of circulatory and airway myeloid cell subsets and related biomarkers in the ...
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