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Large-scale EEG network alterations in late-onset epilepsy of unknown etiology: A comparative study with Alzheimer's disease
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Progressive choroid plexus enlargement across disease stages in patients with sporadic amyotrophic lateral sclerosis
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Capillary stalling: A common microvascular pathway to stroke susceptibility and poor recovery
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Analysis of the involvement of RNA-binding proteins in TAU-dependent neurodegeneration
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De novo variants in MAGED1 suggest a role in intellectual disability pathogenesis
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ROS-HIF1α-driven glycolytic reprogramming sustains ATP production in Huntington's disease
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Cortical network resilience to transient anoxia involves redistribution of single-neuron firing
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Ex vivo T2*-weighted MRI and quantitative susceptibility mapping reflect spatial iron accumulation observed on histology in frontotemporal lobar degeneration
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Cerebellar GABA and executive function among adult female carriers of the fragile X messenger ribonucleoprotein 1 premutation: a pilot study to examine neural underpinnings of the clinical phenotype
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Npc1 deficiency impairs brain vascular integrity in mouse model of Niemann-Pick disease type C1
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Alterations in gene expression and protein levels of extracellular matrix-related molecules in major depressive disorder: Insights from analyses in the hippocampus and prefrontal cortex
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Maternal anti-collapsin response mediator protein 1 antibody inducing autism-like behaviors in offspring
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A phenylketonuria mouse model exhibits EEG spike-wave discharges: Effects of sleep deprivation and low-Phe diet
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Synaptic dysfunction-related gene expression spatially correlates with widespread cortical network atrophy in temporal lobe epilepsy
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Hippocampal APOE/S1P axis regulates synaptic and behavioral deficits in a mouse model of autism
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Early-onset neuroinflammation drives neurodegeneration caused by lysosomal PI(3,5)P2 insufficiency
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PBMC DEG/miRNA biomarkers of TDP-43 pathology in ALS
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Immune receptor LAG3 regulates microglia function during Alzheimer's disease
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Human TDP-43 expression worsens FTD-related phenotypes in progranulin-insufficient mice
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The multifaceted role of B cells in traumatic spinal cord injury: Antibody-dependent and antibody-independent mechanisms
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Gut transit and gut microbiome changes occur prior to the onset of motor impairment in a mouse model of Machado-Joseph disease
The 16S rRNA gene sequence data generated and analysed during the current study are available in the National Centre for B...
Single nucleus RNA sequencing unveils relationship between microglia and endothelial cells in mixed Alzheimer's disease and vascular pathology
Volume 216, November 2025, 107128Author links open overlay panel, , , , , , , , , , Highlights•Expression of receptors P2R...
Altered APP trafficking drives amyloidogenic processing in primary neurons from the AppNL-F knock-in mouse model of Alzheimer's disease
Volume 216, November 2025, 107129Author links open overlay panel, , , , , Highlights•Super-resolution microscopy truly res...
Comparison of neuron-derived extracellular vesicles miRNA profile between patients with behavioural variant frontotemporal dementia and primary psychiatric disorders
The behavioural variant of frontotemporal dementia (bvFTD) often overlaps clinically with primary psychiatric disorders (P...
Cannabidiol releases CB1R from A2AR repression in ischemic stroke
Cannabidiol (CBD) is a phytocannabinoid with potential in one of the most prevalent syndromes occurring at birth, the hypo...
PKR-driven ISR signaling controls synaptic translation and structural plasticity in an age-dependent manner
The integrated stress response (ISR) modulates protein homeostasis in response to both intracellular and extracellular sig...
Enrichment of phosphorylated Tau 181 levels in tear fluid-derived extracellular vesicles
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular amyloid-β (Aβ) plaques and intrace...
APOE4 carriership status influences [11C]PiB white matter retention in cognitively healthy older adults
PurposeThe objective of this study was to assess whether APOE4 carriership status affects white matter (WM) [11C]PiB posit...
An in vivo PET/CT investigation of mitochondrial complex 1, sigma 1, and synaptic vesicle 2 A in patients with amyotrophic lateral sclerosis
BackgroundAmyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder which pathology is still largely...
A novel post-witness social defeat stress model induces robust dorsal hippocampal synaptic and behavioral deficits
Chronic stress disrupts brain homeostasis, contributing to cognitive and emotional dysfunction in patients with psychiatri...
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