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Impaired theta and low-gamma directed information flow in the hippocampal-prefrontal circuit underlies working memory deficits in APP/PS1 mice
Impaired theta and low-gamma directed information flow in the hippocampal-prefrontal circuit underlies working memory deficits in APP/PS1 mice
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline. Working mem...
Knockout of Bmal1 in dopaminergic neurons induces ADHD-like symptoms via hyperactive dopamine signaling in male mice
Knockout of Bmal1 in dopaminergic neurons induces ADHD-like symptoms via hyperactive dopamine signaling in male mice
The central circadian clock coordinates daily oscillations in physiology, metabolism and behavior. Disruptions to core cir...
Chronic lipopolysaccharide exposure promotes cognitive impairments by activating TRPC6-AIM2 inflammasome signaling and the regulation of ginsenoside Rg1 in Trpc6−/− mice
Chronic lipopolysaccharide exposure promotes cognitive impairments by activating TRPC6-AIM2 inflammasome signaling and the regulation of ginsenoside Rg1 in Trpc6−/− mice
Chronic neuroinflammation is a pivotal pathogenesis in neurodegenerative diseases (NDDs). Transient receptor potential can...
Role of astrocytic mu-opioid receptors of the ventrolateral periaqueductal gray in modulating anxiety-like responses
Role of astrocytic mu-opioid receptors of the ventrolateral periaqueductal gray in modulating anxiety-like responses
Mu-opioid receptors (MORs) are critical regulators mediating the modulation of several behavioral reactions, including ana...
C18:0 GM3 ganglioside’s efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation
C18:0 GM3 ganglioside’s efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation
Parkinson’s disease (PD) is an incurable neurological disorder, and current pharmacological therapies primarily addr...
Cutibacterium Acnes induces Alzheimer’s disease-like pathology in brains of wistar rats through structural changes associated with microtubules
Cutibacterium Acnes induces Alzheimer’s disease-like pathology in brains of wistar rats through structural changes associated with microtubules
Cutibacterium acnes(C. acnes), a Gram-positive anaerobe and a dominant bacterium species in the sebaceous follicles of the...
Spectral tuning and after-effects in neural entrainment
Spectral tuning and after-effects in neural entrainment
Neural entrainment has become a popular technique to non-invasively manipulate brain rhythms via external, periodic stimul...
Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala
Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala
Mood disorders, particularly depression and anxiety, are associated with zinc dyshomeostasis and aberrant GABAergic signal...
Uncovering hidden prosocial behaviors underlying aggression motivation in mice and young children
Uncovering hidden prosocial behaviors underlying aggression motivation in mice and young children
Animals exhibit a wide range of social behaviors, including positive actions that promote social cohesion and negative beh...
Reactivity of the ventromedial prefrontal cortex, but not the amygdala, to negative emotion faces predicts greed personality trait
Reactivity of the ventromedial prefrontal cortex, but not the amygdala, to negative emotion faces predicts greed personality trait
This study explored whether amygdala reactivity predicted the greed personality trait (GPT) using both task-based and rest...
Specific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder
Specific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder
Autistic traits (ATs) are frequently reported in children with Attention-Deficit/Hyperactivity Disorder (ADHD). This study...
Mapping the neuroanatomical abnormalities in a phenotype of male compulsive rats
Mapping the neuroanatomical abnormalities in a phenotype of male compulsive rats
Compulsivity is considered a transdiagnostic dimension in obsessive–compulsive and related disorders, characterized ...
Multivariate multiscale entropy (mMSE) as a tool for understanding the resting-state EEG signal dynamics: the spatial distribution and sex/gender-related differences
Multivariate multiscale entropy (mMSE) as a tool for understanding the resting-state EEG signal dynamics: the spatial distribution and sex/gender-related differences
The study aimed to determine how the resting-state EEG (rsEEG) complexity changes both over time and space (channels). The...
Causal associations between sleep traits and brain structure: a bidirectional Mendelian randomization study
Causal associations between sleep traits and brain structure: a bidirectional Mendelian randomization study
Emerging evidence suggests bidirectional causal relationships between sleep disturbance and psychiatric disorders, but the...
Well-being is associated with cortical thickness network topology of human brain
Well-being is associated with cortical thickness network topology of human brain
Living a happy and meaningful life is an eternal topic in positive psychology, which is crucial for individuals’ phy...
Transcranial magnetic stimulation and transcranial direct current stimulation affect explicit but not implicit emotion regulation: a meta-analysis
Transcranial magnetic stimulation and transcranial direct current stimulation affect explicit but not implicit emotion regulation: a meta-analysis
Emotion regulation (ER) refers to the process through which people influence the occurrence, experience, and expression of...
Ocular and neural genes jointly regulate the visuospatial working memory in ADHD children
Ocular and neural genes jointly regulate the visuospatial working memory in ADHD children
Working memory (WM) deficits have frequently been linked to attention deficit hyperactivity disorder (ADHD). Despite previ...
Enhancement of dynamic visual acuity using transcranial alternating current stimulation with gamma burst entrained on alpha wave troughs
Enhancement of dynamic visual acuity using transcranial alternating current stimulation with gamma burst entrained on alpha wave troughs
Cross-frequency phase-amplitude coupling (PAC) of cortical oscillations is observed within and across cortical regions dur...
The mediating role of default mode network during meaning-making aroused by mental simulation between stressful events and stress-related growth: a task fMRI study
The mediating role of default mode network during meaning-making aroused by mental simulation between stressful events and stress-related growth: a task fMRI study
Stressful events and meaning-making toward them play an important role in adolescents’ life and growth. However, ign...
Optogenetic stimulation of basal forebrain cholinergic neurons prevents neuroinflammation and neuropsychiatric manifestations in pristane induced lupus mice
Optogenetic stimulation of basal forebrain cholinergic neurons prevents neuroinflammation and neuropsychiatric manifestations in pristane induced lupus mice
Neuroinflammation has been identified as one of the primary pathogenic factors of neuropsychiatric systemic lupus erythema...
Cumulative genetic score of KIAA0319 affects reading ability in Chinese children: moderation by parental education and mediation by rapid automatized naming
Cumulative genetic score of KIAA0319 affects reading ability in Chinese children: moderation by parental education and mediation by rapid automatized naming
KIAA0319, a well-studied candidate gene, has been shown to be associated with reading ability and developmental dyslexia. ...
Oleoylethanolamide attenuates cocaine-primed reinstatement and alters dopaminergic gene expression in the striatum
Oleoylethanolamide attenuates cocaine-primed reinstatement and alters dopaminergic gene expression in the striatum
The lipid oleoylethanolamide (OEA) has been shown to affect reward-related behavior. However, there is limited experimenta...
Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice
Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice
Alzheimer's disease is accompanied by an abnormal high accumulation of cis-P tau. However, the long-term changes in be...
Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
Increasing evidence has shown that the NOD-like receptor protein 1 (NLRP1) inflammasome is associated with Aβ generat...
Whole-body vibration ameliorates glial pathological changes in the hippocampus of hAPP transgenic mice, but does not affect plaque load
Whole-body vibration ameliorates glial pathological changes in the hippocampus of hAPP transgenic mice, but does not affect plaque load
Alzheimer’s disease (AD) is the core cause of dementia in elderly populations. One of the main hallmarks of AD is ex...
Distinct reinforcement learning profiles distinguish between language and attentional neurodevelopmental disorders
Distinct reinforcement learning profiles distinguish between language and attentional neurodevelopmental disorders
Theoretical models posit abnormalities in cortico-striatal pathways in two of the most common neurodevelopmental ...
Pristane induced lupus mice as a model for neuropsychiatric lupus (NPSLE)
Pristane induced lupus mice as a model for neuropsychiatric lupus (NPSLE)
The pristane-induced lupus (PIL) model is a useful tool for studying environmental-related systemic lupus erythematosus (S...
Previous experience with delays affects delay discounting in animal model of ADHD
Previous experience with delays affects delay discounting in animal model of ADHD
ADHD is a disorder where a common symptom is impulsive behaviour, a broad term associated with making sub-optimal choices....
Increased basolateral amygdala metabolic activity during flavor familiarization: an experimental study
Increased basolateral amygdala metabolic activity during flavor familiarization: an experimental study
Novel flavors elicit a cautious neophobic response which is attenuated as the flavor becomes familiar and safe. The attenu...
Effect of combination fluoxetine and exercise on prefrontal BDNF, anxiety-like behavior and fear extinction in a female rat model of post-traumatic stress disorder (PTSD): a comparison with male animals
Effect of combination fluoxetine and exercise on prefrontal BDNF, anxiety-like behavior and fear extinction in a female rat model of post-traumatic stress disorder (PTSD): a comparison with male animals
Despite significant differences between men and women in the symptoms of PTSD and the response to therapeutic intervention...
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