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SCI Abstract
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Heart Failure with Preserved Ejection Fraction as a Risk Factor for Atrial Fibrillation Recurrence after Ablation
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Potentially Clinically Significant Drug-Drug Interactions in Older Adults with Atrial Fibrillation and Multimorbidity: Prevalence, Correlates, and Association with Adverse Clinical Outcomes in a Swedish National Register-Based Study
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Mitochondria at the Heart of Ischemia-Reperfusion (I/R) Injury: the HOXB5-Sirt5 Axis
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Protective Effects of Jiawei Baihu Tang in Kawasaki Disease: Omics Analysis and Mechanistic Exploration
Kawasaki disease (KD) is classified as a “WenBing” syndrome in traditional Chinese medicine (TCM), characteriz...
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Targeting SIRT3 in Diabetic Cardiomyopathy: Mechanism-Based Therapeutic Strategies
Diabetic cardiomyopathy (DCM) represents a prevalent and clinically significant complication associated with diabetes mell...
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N-Lac-Phe Ameliorates Myocardial Cell Death by Improving Mitochondrial Dysfunction, Ultimately Improving TAC-induced Heart Failure
Mitochondrial dysfunction and cardiomyocyte death drive pressure overload-induced heart failure (HF). N-lactylphenylalanin...
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Lipoprotein (a) and Coronary Atherosclerosis in Intracoronary Imaging - YELLOW II – Lp(a) Study
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Dapagliflozin Inhibits Thrombin Induced ADAM17 Phosphorylation and Downstream ERK/p-c-Jun-mediated CTGF Induction to Prevent Neointimal Hyperplasia
Vascular restenosis following angioplasty remains a major clinical challenge driven by excessive vascular smooth muscle ce...
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Cardioprotection Through Mitochondrial Modulation: A Systematic Review of Pharmacological Interventions in Animal Models of I/R Injury
Myocardial reperfusion following ischaemia paradoxically exacerbates mitochondrial and thus cardiac dysfunction. Although ...
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Hyperuricemia and Hypoxic Pulmonary Hypertension: Pathogenic Links, Clinical Evidence, and Emerging Therapeutic Insights
This review aims to explore the role of hyperuricemia in the pathogenesis of hypoxic pulmonary hypertension (HPH), focusin...
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Therapeutic Ultrasound in Cardiovascular Medicine: Applications of Low-intensity Pulsed Ultrasound and Ultrasound-targeted Microbubble Destruction
Cardiovascular disease (CVD) represents a significant global health challenge, with its high incidence and mortality rates...
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Minimally Invasive Trans-atrial Mitral Valve Replacement Using a Balloon-expandable Transcatheter Valve in the Setting of Severe Mitral Annular Calcification
Severe mitral annular calcification (MAC) increases the complexity and risk of conventional mitral valve replacement (MVR)...
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Effects of Angiotensin-Converting Enzyme Inhibitors/Angiotensin II Receptor Blockers on Prognosis in Acute Coronary Syndrome Patients with Preserved Ejection Fraction Undergoing Regular Dialysis
The utilization of angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker (ARB) following myoca...
Cardiovascular Drugs And Therapy
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Pericardial Administration of Extracellular Vesicles Derived from Bone Marrow Stem Cells Improved Doxorubicin-induced Heart Failure with Mid Range Ejection Fraction (HFmrEF) in Rats
This study investigates the therapeutic effects of extracellular vesicles (EVs) derived from bone marrow mesenchymal stem ...
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Molecular Interplay of Gene Network Dynamics, Epigenetic Regulation, and Therapeutic Mapping in Cardiovascular Disease
Cardiovascular diseases (CVDs) continue to be the leading cause of death globally, driven by a complex interplay of geneti...
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Impact of Percutaneous Coronary Interventions on Coronary Microvascular System: Coronary Stenting Versus Drug-Coated Balloon Angioplasty
Authors and AffiliationsDepartment of Cardiology, School of Medicine, Trakya University, Edirne, 22030, TurkeyUğur Özkan, ...
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Clinical Implication of Quantitative Flow Ratio to Predict Clinical Outcomes in De Novo Coronary Lesions After Drug-Coated Balloon Angioplasty
The association between the intra-procedure quantitative flow ratio (QFR) and clinical outcomes after drug-coated balloon ...
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Direct Oral Anticoagulants in Valvular Diseases and Prosthetic Valves: Why Not?
Valvular heart disease (VHD) and atrial fibrillation (AF) often coexist and lead to a prothrombotic state that necessitate...
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Factor XIa Inhibitors Versus Direct Oral Anticoagulants for Atrial Fibrillation: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Direct oral anticoagulants (DOACs) are the standard treatment for reducing thromboembolic risk in patients with atrial fib...
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Correction to: Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts
Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029...
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The Emerging Role of Lactate and Lactylation Modifications in the Pathophysiology of Atherosclerotic Cardiovascular Diseases
Atherosclerosis is a chronic disease that is characterized by lipid accumulation and inflammation in the arterial wall. At...
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Resuscitative Mean Arterial Pressure Targets in Cardiovascular Disease: A Narrative Review of Clinical Outcomes
Mean arterial pressure (MAP) is a commonly used hemodynamic proxy for tissue perfusion. Continuous MAP monitoring and main...
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GLP1-RA and SGLT2-i: Implementation and Insulin Deescalation Strategies
This review will summarize the most contemporary trials for glucagon-like peptide 1 receptor agonists (GLP1-RA) and sodium...
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Real-World Efficacy of Inclisiran in Veneto Region (Italy): The INCLIVEN Multicenter Registry
Inclisiran is a long-acting small interfering RNA (siRNA) which prevents the synthesis of PCSK9 in hepatocytes, reducing L...
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AGE-RAGE Axis and Cardiovascular Diseases: Pathophysiologic Mechanisms and Prospects for Clinical Applications
Advanced glycation end products (AGE), a diverse array of molecules generated through non-enzymatic glycosylation, in conj...
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Epicardial Adipocytes in Cardiac Pathology and Healing
Implications of epicardial adipose tissue (EAT) on the development of coronary artery disease (CAD) have garnered recent a...
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The Incidence of Contrast-Induced Nephropathy in Patients on Sodium-Glucose Cotransporter-2 Inhibitors Following Percutaneous Coronary Intervention: An Observational Analysis
The purpose of this study is to compare the incidence of contrast-induced nephropathy (CIN) following percutaneous coronar...
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Associations of SGLT2i with Cardiorenal Outcomes Among Diabetics with Prostate Cancer on Hormone Therapy
Studies have reported associations between prostate cancer, type II diabetes mellitus (T2DM), and cardiovascular disease i...
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Kirenol Ameliorates Myocardial Ischemia–Reperfusion Injury by Promoting Mitochondrial Function and Inhibiting Inflammasome Activation
Macrophage-mediated inflammation plays a crucial role in the pathophysiological process of myocardial ischemia/reperfusion...
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Ticagrelor versus Clopidogrel: Two Controversial Drugs in Patients with Acute Coronary Syndrome
Yan Y, Xu H, Zhao Y, Lin S, Zheng Y. Ticagrelor versus clopidogrel in patients with left main coronary artery stenting. Ca...
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