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Label‐free 3D characterization of cardiac fibrosis in muscular dystrophy using SHG imaging of cleared tissue
Label‐free 3D characterization of cardiac fibrosis in muscular dystrophy using SHG imaging of cleared tissue
Abstract Background information Duchenne muscular dystrophy (DMD) is a neuromuscular disease caused by mutations in the ge...
Human breast tumor derived endothelial cells exhibit distinct biological properties
Human breast tumor derived endothelial cells exhibit distinct biological properties
Background Information : Excessive angiogenesis characterized by leaky, tortuous and chaotic vasculature is one of the hal...
How palmitoylation affects trafficking and signaling of membrane receptors
How palmitoylation affects trafficking and signaling of membrane receptors
Abstract S-acylation (or palmitoylation) is a reversible post-translational modification (PTM) that modulates protein acti...
How palmitoylation affects trafficking and signalling of membrane receptors
How palmitoylation affects trafficking and signalling of membrane receptors
Abstract S-acylation (or palmitoylation) is a reversible post-translational modification (PTM) that modulates protein acti...
Endocytosis and stress: From mechanisms to cellular physiology
Endocytosis and stress: From mechanisms to cellular physiology
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Alpha‐arrestins Aly1/Art6 and Aly2/Art3 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis
Alpha‐arrestins Aly1/Art6 and Aly2/Art3 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis
Abstract Background information Phosphatidylinositol (PI) is an essential phospholipid, critical to membrane bilayers. The...
A new pancreatic adenocarcinoma‐derived organoid model of acquired chemoresistance to FOLFIRINOX: first insight of the underlying mechanisms
A new pancreatic adenocarcinoma‐derived organoid model of acquired chemoresistance to FOLFIRINOX: first insight of the underlying mechanisms
Background information Although improvements have been made in the management of pancreatic adenocarcinoma (PDAC) during t...
Alpha‐arrestins Aly1 and Aly2 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis
Alpha‐arrestins Aly1 and Aly2 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis
Phosphatidylinositol (PI) is an essential phospholipid, critical to membrane bilayers. The complete deacylation of PI by B...
Bioengineering methods for organoid systems
Bioengineering methods for organoid systems
Abstract Organoids have been widely used in fundamental, biomimetic and therapeutic studies. These multicellular systems f...
Decreased proliferation of aged rat beta cells corresponds with enhanced expression of the cell cycle inhibitor p27KIP1
Decreased proliferation of aged rat beta cells corresponds with enhanced expression of the cell cycle inhibitor p27KIP1
Abstract Background Over 400 million people are diabetic. Type 1 and type 2 diabetes are characterized by decreased functi...
Role of regulatory C‐terminal motifs in synaptic confinement of LRRTM2
Role of regulatory C‐terminal motifs in synaptic confinement of LRRTM2
Abstract Leucine Rich Repeat Transmembrane proteins (LRRTMs) are neuronal cell adhesion molecules involved in synapse deve...
Apoptosis induction by the stem cell factor LIN28A
Apoptosis induction by the stem cell factor LIN28A
Abstract Background information Lin28A and its paralog Lin28B are RNA binding proteins expressed in stem and progenitor ce...
Apoptosis induction by the stem cell factor LIN28
Apoptosis induction by the stem cell factor LIN28
Lin28A and its paralog Lin28B are RNA binding proteins expressed in stem and progenitor cells, regulating the balance betw...
Quantitative dSTORM super‐resolution microscopy localizes Aurora kinase A/AURKA in the mitochondrial matrix
Quantitative dSTORM super‐resolution microscopy localizes Aurora kinase A/AURKA in the mitochondrial matrix
Abstract Mitochondria are dynamic organelles playing essential metabolic and signaling functions in cells. Their ultrastru...
Direct measurement of near‐nano‐Newton forces developed by self‐organizing actomyosin fibers bound α‐catenin
Direct measurement of near‐nano‐Newton forces developed by self‐organizing actomyosin fibers bound α‐catenin
Background Information Actin cytoskeleton contractility plays a critical role in morphogenetic processes by generating for...
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