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Dynamic GTPase networks reshaping endosomal organelle identities
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Homeostatic responses to diverse cellular stresses by the ER-Golgi trafficking pathways
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Emerging mechanisms of COPII adaptation for large cargo ER export
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Functions and regulated material states of cytoskeletal condensates
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Serotonin (5-HT): ancient signaling molecule reshaped by serotonylation in cancer
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Ageing influences tumour–niche interactions: Implications for metastatic dormancy, reawakening and recurrence
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Cancer signaling beyond the genes
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The formation, dynamics, and disassembly of caveolae
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CoCB cell signalling 2024
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Decoding metastasis initiation through spatiotemporal extracellular vesicle-mediated intercellular signaling
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A waxy path: Lipid dynamics during tuberculosis
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The interplay of lipid droplets, mitochondria, and ER in governing hepatic lipid metabolism
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The broad spectrum of myeloid cell migration strategies
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Signaling lipids: An overview of emerging physiological functions
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Encoding chemical cues through compartmentalized signal packaging
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Building the autophagosome: Molecular logic and membrane dynamics of autophagy
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I did it my way: the origins of lipid droplet heterogeneity
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Substrate selectivity as a paradigm shift in mTORC1 signaling
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Controlling cell architecture with protein design
Cells depend on a complex and precisely regulated subcellular organization, largely driven by the cytoskeleton and motor p...
Cytoskeletal scaffolding of NaVs and KVs in neocortical pyramidal neurons: Implications for neuronal signaling and plasticity
The initiation and propagation of action potentials (APs) depend on the precise localization of voltage-gated sodium (NaV)...
Leveraging phylogenetic diversity: Cellular dynamics in non-model organisms
Cell biologists use a severely undersampled population of eukaryotes as model organisms to infer cellular processes across...
KASH proteins transform from passive tethers to dynamic conductors of motor-driven nuclear dynamics
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Mechanisms of transmembrane domain recognition during endoplasmic reticulum quality control
Misfolded proteins can be toxic to cells, and their accumulation is a hallmark of diseases such as neurodegeneration. Norm...
Signaling mechanisms in the reactivation of quiescent neural stem cells in Drosophila
Neural stem cells (NSCs) play a central role in the nervous system development and regeneration. In the adult mammalian br...
Cancer-associated fibroblasts as mediators of tissue microenvironment remodeling in cancer
Cancer-associated fibroblasts (CAFs) are a multifunctional cell population of solid tumors that substantially remodel the ...
Mechanisms of cellular fitness and cell competition: Towards an integrated view
Cell competition is a fundamental mechanism of tissue quality control that enables the selective elimination of less fit, ...
Epigenetic regulation of DUX4: From embryogenesis to muscular degeneration
DUX4 is a transcription factor with a critical role in zygotic genome activation. It is expressed briefly in early embryog...
When two worlds collide: actin dynamics on endomembranes regulates membrane trafficking
Membrane trafficking is an essential aspect of cellular physiology, determining the spatial distribution of macromolecules...
Cell signaling across scales in health and disease
Victoria Sanz Moreno is a Professor of Cancer Cell and Metastasis Biology at the Institute of Cancer Research in London. H...