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Transforming growth factor-beta (TGF-β) mediated induction of miR-21-5p drives oral squamous cell carcinoma (OSCC) progression through suppression of KLF5
Transforming growth factor-beta (TGF-β) mediated induction of miR-21-5p drives oral squamous cell carcinoma (OSCC) progression through suppression of KLF5
Oral squamous cell carcinoma (OSCC) is the most common aggressive malignancy of the head and neck squamous cell carcinoma ...
In vitro cleavage validation assay of myostatin gene by CRISPR-Cas9 ribonucleoprotein complex: from PCR amplification to cleavage assay
In vitro cleavage validation assay of myostatin gene by CRISPR-Cas9 ribonucleoprotein complex: from PCR amplification to cleavage assay
The primary experimental objective of the present investigation is to study the targeted genome editing of the myostatin (...
Forensic efficacy evaluation of the Microreader™ 28 A ID System in Indian subpopulation
Forensic efficacy evaluation of the Microreader™ 28 A ID System in Indian subpopulation
The state of Haryana in India is known for its archaeological sites related to the Indus Valley Civilisation and is a regi...
Multi-trait genotypic stability and performance assessment in kodo millet ( mutants employing AMMI, MGIDI and MTSI indices
Multi-trait genotypic stability and performance assessment in kodo millet ( mutants employing AMMI, MGIDI and MTSI indices
Kodo millet (Paspalum scrobiculatum L.) is a nutrient-rich and climate-resilient crop. Its productivity is often constrain...
A 27-year retrospective analysis of 24,633 cases reveals the spectrum of chromosomal abnormalities in Southern India and identifies a novel translocation disrupting EFCAB3
A 27-year retrospective analysis of 24,633 cases reveals the spectrum of chromosomal abnormalities in Southern India and identifies a novel translocation disrupting EFCAB3
Chromosomal rearrangements are a major cause of human disorders. They can be numerical or structural abnormalities, and un...
Inverted meiosis and holocentric chromosome behaviour in (Convolvulaceae), an endemic dodder species of the Western Ghats, India
Inverted meiosis and holocentric chromosome behaviour in (Convolvulaceae), an endemic dodder species of the Western Ghats, India
Cuscuta janarthanamii Kolte, A. Deshp. & Kambale, a recently described species, has been investigated for its chro...
Polymorphism analysis and development of PCR-based haplotype-linked markers for the gene associated with enhanced kernel iron content in subtropical maize
Polymorphism analysis and development of PCR-based haplotype-linked markers for the gene associated with enhanced kernel iron content in subtropical maize
Iron deficiency, impacting more than half of the global population, poses a major health concern and contributing factor f...
Genome wide identification of hard and soft selective sweeps reveals distinct selection signatures in Karan Fries cattle
Genome wide identification of hard and soft selective sweeps reveals distinct selection signatures in Karan Fries cattle
Natural selection shapes the genome by favoring beneficial mutations, leading to selective sweeps through the hitchhiking ...
The karyotypic landscape of Holocentridae: unveiling patterns of chromosomal evolution in a reef fish family
The karyotypic landscape of Holocentridae: unveiling patterns of chromosomal evolution in a reef fish family
The squirrelfish family (Holocentridae) represents a ubiquitous and ecologically vital component of coral reef fauna. Thei...
Contrasting genomic architectures and linkage disequilibrium landscapes with insights into adaptive potential of Sahiwal and Kangayam cattle from whole-genome resequencing
Contrasting genomic architectures and linkage disequilibrium landscapes with insights into adaptive potential of Sahiwal and Kangayam cattle from whole-genome resequencing
This study presents a whole-genome re-sequencing (WGR) analysis of two genetically and functionally distinct indigenous In...
The interplay between autophagy and microRNAs in kidney diseases: possible therapeutic crosstalk for targeted therapy
The interplay between autophagy and microRNAs in kidney diseases: possible therapeutic crosstalk for targeted therapy
The interplay between autophagy and microRNAs (miRNAs) has emerged as a pivotal regulatory axis in the pathogenesis of kid...
Genetic predisposition to gastric cancer and treatment outcomes in South Asian and Iranian populations: a comprehensive meta-analysis
Genetic predisposition to gastric cancer and treatment outcomes in South Asian and Iranian populations: a comprehensive meta-analysis
Gastric cancer (GC) represents a major health burden in South Asia and Iran, with genetic susceptibility varying substanti...
CRM1 as a potential biomarker and therapeutic target in cancer: a comprehensive review
CRM1 as a potential biomarker and therapeutic target in cancer: a comprehensive review
Chromosome region maintenance 1 (CRM1) is a key nuclear export receptor that mediates the transport of numerous proteins a...
Late embryogenesis protein (LEA): not so late for plants under stress
Late embryogenesis protein (LEA): not so late for plants under stress
Plant encounters several abiotic and biotic stresses during their life cycle which effect their growth and development. So...
miR-23 has been identified as a blood biomarker useful for estrus identification in Indian river buffaloes ()
miR-23 has been identified as a blood biomarker useful for estrus identification in Indian river buffaloes ()
Silent estrus remains a significant barrier to efficient reproductive management in buffaloes, resulting in missed breedin...
Advancements in liquid biopsy for gastrointestinal cancers receiving RTK-targeted therapies: Predicting treatment response and monitoring disease progression
Advancements in liquid biopsy for gastrointestinal cancers receiving RTK-targeted therapies: Predicting treatment response and monitoring disease progression
Receptor tyrosine kinase (RTK) inhibitors have transformed the therapeutic landscape of gastrointestinal (GI) cancers, yet...
Development and evaluation of sub-tropically adapted sweet corn hybrids for dual-purpose utilization with emphasis on yield and fodder quality traits
Development and evaluation of sub-tropically adapted sweet corn hybrids for dual-purpose utilization with emphasis on yield and fodder quality traits
Sweet corn is increasingly valued as a dual-purpose crop providing both edible cobs and nutritious green fodder; however, ...
Oxidative imbalance, mitotic inhibition, and DNA damage in early development of lettuce induced by Benth. (Fabaceae) aqueous extract
Oxidative imbalance, mitotic inhibition, and DNA damage in early development of lettuce induced by Benth. (Fabaceae) aqueous extract
Allelopathic compounds from native plants are promising environmentally sustainable alternatives for weed management. This...
First report on mediated green synthesis and characterization of copper nanoparticles with potent anticancer activity against MDA-MB-231 cells
First report on mediated green synthesis and characterization of copper nanoparticles with potent anticancer activity against MDA-MB-231 cells
A novel green synthesis approach was developed for the fabrication of copper nanoparticles (CuNPs) using leaf extract of J...
Association of two LEP gene SNPs with reproductive performance in pigs: Potential markers for genetic selection
Association of two LEP gene SNPs with reproductive performance in pigs: Potential markers for genetic selection
The leptin (LEP) gene plays a key role in fat metabolism, energy balance, and reproductive performance in pigs. This study...
-Topolin as an effective cytokinin for high-frequency regeneration and clonal fidelity in Jacq. cv. Naga Chili
-Topolin as an effective cytokinin for high-frequency regeneration and clonal fidelity in Jacq. cv. Naga Chili
The plant Capsicum chinense Jacq. cv. Naga King Chili, a significant horticultural crop of Nagaland in North-east India, i...
Association of IL22 and C4A gene with production and udder conformation traits in Sahiwal () and Karan Fries ( x ) cattle
Association of IL22 and C4A gene with production and udder conformation traits in Sahiwal () and Karan Fries ( x ) cattle
Linear type traits are important for animal breeders for making selection decision in dairy cattle because of their signif...
, and genes association with vegetative stage drought stress in rice validated through mendelian randomization
, and genes association with vegetative stage drought stress in rice validated through mendelian randomization
In rice, NCED2, NAM, DEC genes have been characterized for their role in yield under aerobic conditions and reproductive s...
gene-specific sequence variation and phylogenetic relationship in aromatic rice ( L.)
gene-specific sequence variation and phylogenetic relationship in aromatic rice ( L.)
Fragrance is the most valued grain quality trait in rice, yet the genetic augmentation for high yield coupled with aroma i...
Richness of SSR marker alleles and their efficiency to discriminate bitter gourd ( L.) advanced breeding lines for their fruit yielding potential
Richness of SSR marker alleles and their efficiency to discriminate bitter gourd ( L.) advanced breeding lines for their fruit yielding potential
Harnessing heterosis through F1 hybrids is one of the most efficient strategies for enhancing productivity of crops includ...
In silico identification of GTPase inhibitors from selected anti-gonorrheal plants against
In silico identification of GTPase inhibitors from selected anti-gonorrheal plants against
The global rise of multidrug-resistant Neisseria gonorrhoeae underscores the urgent need for innovative ...
Longitudinal genomic and pedigree inbreeding metrics reveal inbreeding depression in milk quality traits of Sahiwal cattle maintained in organised herd
Longitudinal genomic and pedigree inbreeding metrics reveal inbreeding depression in milk quality traits of Sahiwal cattle maintained in organised herd
The selection of individuals depends on their predicted breeding values and mating of related individuals that might enhan...
Unravelling the UV-B response in two species: biochemical and molecular insights into and
Unravelling the UV-B response in two species: biochemical and molecular insights into and
Withania is majorly known by its two commercially significant species i.e., W. somnifera and W. coagulans. While both the ...
Allele mining for the candidate genes regulating parthenocarpy in cucumber ( L.)
Allele mining for the candidate genes regulating parthenocarpy in cucumber ( L.)
Naturally occurring allelic variation was mined for genes responsible for controlling parthenocarpy in cucumber. During th...
Inheritance of resistance to tomato leaf curl New Delhi virus in cucumber ( L.) utilizing parthenocarpic, gynoecious, and monoecious lines in Northern plains of India
Inheritance of resistance to tomato leaf curl New Delhi virus in cucumber ( L.) utilizing parthenocarpic, gynoecious, and monoecious lines in Northern plains of India
Tomato leaf curl New Delhi virus (ToLCNDV) is the most destructive whitefly transmitted “single-stranded DNA begomov...
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