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A population-based cohort to evaluate drug safety during pregnancy (PREGVAL): rationale, design, and baseline characteristics
A population-based cohort to evaluate drug safety during pregnancy (PREGVAL): rationale, design, and baseline characteristics
The main aim of the PREGVAL cohort is to evaluate and monitor the in-utero safety of medication administered to pregnant w...
Cohort profile: the Guangzhou older longitudinal dynamic health (GOLD-Health) cohort
Cohort profile: the Guangzhou older longitudinal dynamic health (GOLD-Health) cohort
The Guangzhou Older Longitudinal Dynamic Health (GOLD-Health) Cohort is a prospective population-based cohort study aimed ...
Fetal programming of early-onset type 2 diabetes: a Swedish nationwide cohort and sibling analysis
Fetal programming of early-onset type 2 diabetes: a Swedish nationwide cohort and sibling analysis
Incidence of early-onset (< 40 years) type 2 diabetes (T2D) is increasing. While multiple risk factors have b...
Traditional and advanced electrocardiographic measures of autonomic function in the population-based KORA-F3 study
Traditional and advanced electrocardiographic measures of autonomic function in the population-based KORA-F3 study
Heart-rate variability (HRV) measures are surrogates of autonomic function at the level of the sinus node and have evolved...
Identification of individuals who benefit from omega-3 fatty acid supplementation to prevent coronary heart disease: a machine-learning analysis of the VITAL
Identification of individuals who benefit from omega-3 fatty acid supplementation to prevent coronary heart disease: a machine-learning analysis of the VITAL
Randomized controlled trials (RCTs) have demonstrated benefits of marine omega-3 polyunsaturated fatty acids (omega-3 FA) ...
How hazard ratios can mislead and why it matters in practice
How hazard ratios can mislead and why it matters in practice
Hazard ratios are routinely reported as effect measures in clinical trials and observational studies. However, many method...
Use of systemic hormonal contraception and risk of depression: a registry-based study from Finland
Use of systemic hormonal contraception and risk of depression: a registry-based study from Finland
Earlier findings on the relationship between use of hormonal contraception (HC) and depressive symptoms and disorders are ...
Ingestion of titanium dioxide as an excipient in medicines and the risk of cancer: a nationwide study within the French National health data system
Ingestion of titanium dioxide as an excipient in medicines and the risk of cancer: a nationwide study within the French National health data system
Concerns about the safety of titanium dioxide (TiO2), including potential carcinogenicity, have prompted its ban in foods ...
TransplantLines, a biobank and cohort study of solid organ transplant recipients and donors
TransplantLines, a biobank and cohort study of solid organ transplant recipients and donors
The TransplantLines Biobank and Cohort Study (NCT03272841) is an ongoing prospective study conducted at the University Med...
Looking at randomized trials with the critical eyes of epidemiologists: the case of screening colonoscopy
Looking at randomized trials with the critical eyes of epidemiologists: the case of screening colonoscopy
Based on compelling evidence from observational epidemiological studies, screening colonoscopy has since long been thought...
Breast Cancer Information Grand Round for Survivorship (BIG-S) prospective cohort
Breast Cancer Information Grand Round for Survivorship (BIG-S) prospective cohort
Existing evidence indicates that long-term effects of breast cancer treatment can significantly impact survivors’ ab...
Oral contraceptive use increases bone density and reduces the risk of osteoporosis
Oral contraceptive use increases bone density and reduces the risk of osteoporosis
Osteoporotic fractures, largely resulting from reduced estrogen levels after menopause and subsequent bone loss, are a lea...
Hormonal contraceptive use and anaemia: a nation-wide pharmacoepidemiological study from Northern Europe
Hormonal contraceptive use and anaemia: a nation-wide pharmacoepidemiological study from Northern Europe
The WHO aims to reduce iron deficiency anaemia globally. Use of modern hormonal contraception (HC) could offer protection ...
COVID-19 infection increases the risk of venous thromboembolism during pregnancy and the postpartum period
COVID-19 infection increases the risk of venous thromboembolism during pregnancy and the postpartum period
Pregnant and puerperal women are at increased risk of venous thromboembolism (VTE) owing to hemostatic changes in preparat...
A phenome-wide association study of genetically determined nicotine metabolism reveals novel links with health-related outcomes
A phenome-wide association study of genetically determined nicotine metabolism reveals novel links with health-related outcomes
Faster nicotine metabolism, defined as the nicotine metabolite ratio (NMR), is known to associate with heavier smoking and...
Plant-based dietary patterns and breast cancer risk in the European prospective investigation into cancer and nutrition (EPIC) study
Plant-based dietary patterns and breast cancer risk in the European prospective investigation into cancer and nutrition (EPIC) study
While previous literature suggests that plant-based diets may be associated with a lower risk of breast cancer, evidence r...
Identifying multiple sclerosis in women of childbearing age in six European countries: a contribution from the ConcePTION project
Identifying multiple sclerosis in women of childbearing age in six European countries: a contribution from the ConcePTION project
Prevalence of Multiple Sclerosis (MS) has increased over the last decades, primarily among women of childbearing age. Seve...
Getting closer to each other? Convergence and divergence patterns of life expectancy in 277 border regions of Western Europe 1995–2019
Getting closer to each other? Convergence and divergence patterns of life expectancy in 277 border regions of Western Europe 1995–2019
This study offers a comprehensive analysis of life expectancy patterns across Western European border regions, using novel...
The SG90 cohort of the oldest-old in Singapore
The SG90 cohort of the oldest-old in Singapore
The global population is ageing rapidly. While genetics, lifestyle, and environment are known contributors to healthspan, ...
The pitfalls of focusing on cardiovascular disease mortality to explain differences in life expectancy
The pitfalls of focusing on cardiovascular disease mortality to explain differences in life expectancy
Third, we think, non-health related factors (attitudes, culture, values) that constitute a population should receive more ...
Cohort profile: the China surgery and anesthesia cohort (CSAC)
Cohort profile: the China surgery and anesthesia cohort (CSAC)
The China Surgery and Anaesthesia Cohort (CSAC) study was launched in July 2020 and is an ongoing prospective cohort study...
A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese men
A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese men
Dietary factors have been extensively investigated as possible risk factors for liver cancer, but the evidence is inconclu...
Agricultural activities and risk of Alzheimer’s disease: the TRACTOR project, a nationwide retrospective cohort study
Agricultural activities and risk of Alzheimer’s disease: the TRACTOR project, a nationwide retrospective cohort study
Data regarding Alzheimer’s disease (AD) occurrence in farming populations is lacking. This study aimed to investigat...
Strong associations of serum selenoprotein P with all-cause mortality and mortality due to cancer, cardiovascular, respiratory and gastrointestinal diseases in older German adults
Strong associations of serum selenoprotein P with all-cause mortality and mortality due to cancer, cardiovascular, respiratory and gastrointestinal diseases in older German adults
Selenium is an essential trace mineral. The main function of selenoprotein P (SELENOP) is to transport selenium but it has...
Menopausal hormone therapy and risk of sarcoidosis: a population-based nested case–control study in Sweden
Menopausal hormone therapy and risk of sarcoidosis: a population-based nested case–control study in Sweden
Sarcoidosis incidence peaks in women between 50 and 60 years old, which coincides with menopause, suggesting that certain ...
Vitamin D and human health: evidence from Mendelian randomization studies
Vitamin D and human health: evidence from Mendelian randomization studies
We summarized the current evidence on vitamin D and major health outcomes from Mendelian randomization (MR) studies. PubMe...
Population-based analysis of the number of thrombectomies performed after cerebral ischemic stroke and prognostic factors of mortality in France
Population-based analysis of the number of thrombectomies performed after cerebral ischemic stroke and prognostic factors of mortality in France
Study designThis retrospective study analyzed data extracted from the standard French national hospital discharge database...
Assessing the importance of primary care diagnoses in the UK Biobank
Assessing the importance of primary care diagnoses in the UK Biobank
The UK Biobank has made general practitioner (GP) data (censoring date 2016–2017) available for approximately 45% of...
Occupational exposure to diesel exhausts and liver and pancreatic cancers: a systematic review and meta-analysis
Occupational exposure to diesel exhausts and liver and pancreatic cancers: a systematic review and meta-analysis
Diesel exhaust (DE) is human carcinogen with sufficient evidence only for lung cancer. Systematic evidence on other cancer...
Does having siblings really protect against childhood atopic diseases? A total population and within-family analysis
Does having siblings really protect against childhood atopic diseases? A total population and within-family analysis
The association between having older siblings and decreased risk for atopic symptoms is well-established. This has been in...
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