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Redox and bioenergetic modulation by plumbagin attenuated neuropathic allodynia in mice with diet-induced diabetes
Painful diabetic neuropathy represents a substantial health burden, afflicting approximately 30% of individuals with diabe...
GULP1 enhances GLUT4 translocation by counteracting ACAP1–ARF6 inhibition
GULP1 enhances GLUT4 translocation by counteracting ACAP1–ARF6 inhibition
The molecular underpinnings of obesity-induced insulin resistance, a key driver of type 2 diabetes mellitus (T2DM), remain...
Defining a ketone threshold for weight loss: evidence from 14 day daily β-hydroxybutyrate monitoring in 217 subjects on a ketogenic diet
The ketogenic diet (KD) is a widely used nutritional intervention for weight loss. The beneficial effects of the KD are in...
Oral microbiota mediates the association of healthy dietary patterns with lower risk of advanced cardiovascular-kidney-metabolic syndrome
Oral microbiota mediates the association of healthy dietary patterns with lower risk of advanced cardiovascular-kidney-metabolic syndrome
Existing evidence links diet and the oral microbiota to individual cardiovascular, kidney, and metabolic conditions, but t...
Long-term time in target range for body mass index (BMI) and diabetes incidence: insights from CHARLS
Long-term time in target range for body mass index (BMI) and diabetes incidence: insights from CHARLS
Body mass index (BMI) is strongly associated with the development of type 2 diabetes. However, the association between lon...
Designing GLP-1 delivery: structural perspectives and formulation approaches for optimized therapy
Designing GLP-1 delivery: structural perspectives and formulation approaches for optimized therapy
GLP-1 and its synthetic analogs have emerged as significant therapeutic agents for the management of metabolic disorders, ...
Global burden of 13 non-communicable diseases attributable to high fasting plasma glucose from the GBD 2021 study
Global burden of 13 non-communicable diseases attributable to high fasting plasma glucose from the GBD 2021 study
High fasting plasma glucose (HFPG) is a major risk factor for diseases, posing a serious public health challenge. This stu...
Pre-clinical studies show anti-diabetic effect of INSPARIN, a protein derived from the E4orf1 gene of a human adenovirus
Pre-clinical studies show anti-diabetic effect of INSPARIN, a protein derived from the E4orf1 gene of a human adenovirus
Human adenovirus Ad36-derived protein, termed INSPARIN, up-regulates cellular glucose uptake through insulin-independent c...
Gestational weight trajectory and early offspring growth differed by gestational diabetes: a population-based cohort study
Gestational weight trajectory and early offspring growth differed by gestational diabetes: a population-based cohort study
To investigate the association of gestational weight gain (GWG) trajectory with early children growth, and explore whether...
A comprehensive review on the implications of Yogic/Sattvic diet in reducing inflammation in type 2 diabetes
A comprehensive review on the implications of Yogic/Sattvic diet in reducing inflammation in type 2 diabetes
Chronic inflammation in type 2 diabetes (T2D), characterized by constitutively activated immune cells and elevated pro-inf...
Novel first-trimester serum biomarkers for early prediction of gestational diabetes mellitus
Novel first-trimester serum biomarkers for early prediction of gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a common obstetric complication worldwide that seriously threatens maternal and fet...
Association between serum beta-hydroxybutyrate levels and risk of type 2 diabetes mellitus in patients with impaired fasting glucose
Association between serum beta-hydroxybutyrate levels and risk of type 2 diabetes mellitus in patients with impaired fasting glucose
Ketogenic conditions have gained attention due to their favorable metabolic prognoses. We aimed to investigate the associa...
Geraniol reverses obesity by improving conversion of WAT to BAT in high fat diet induced obese rats by inhibiting HMGCoA reductase
Geraniol reverses obesity by improving conversion of WAT to BAT in high fat diet induced obese rats by inhibiting HMGCoA reductase
Present report evaluates the protective effect of geraniol on high fat diet (HFD) induced obesity in rats and also determi...
Urolithin C alleviates pancreatic β-cell dysfunction in type 1 diabetes by activating Nrf2 signaling
Urolithin C alleviates pancreatic β-cell dysfunction in type 1 diabetes by activating Nrf2 signaling
Type 1 diabetes (T1D) is an autoimmune disorder that destroys insulin-generating pancreatic β-cells. Preserving pancr...
Metabolic associated fatty liver disease and sarcopenia additively increase mortality: a real-world study
Metabolic associated fatty liver disease and sarcopenia additively increase mortality: a real-world study
Sarcopenia is associated with worse prognosis for non-alcoholic fatty liver disease (NAFLD). However, disease progression ...