SCI Abstract

search
+
Development of a core descriptor set for studies assessing interventions for diabetes-related foot ulceration
Development of a core descriptor set for studies assessing interventions for diabetes-related foot ulceration
Foot ulceration is a common complication of diabetes and is associated with high mortality and costs. The quality of evide...
Association of long-term exposure to air pollution, built environment and air temperature with the incidence of prediabetes phenotypes, and prediabetes remission and progression to type 2 diabetes: a longitudinal study in the KORA cohort
Association of long-term exposure to air pollution, built environment and air temperature with the incidence of prediabetes phenotypes, and prediabetes remission and progression to type 2 diabetes: a longitudinal study in the KORA cohort
Environmental exposures have been adversely associated with the risk of diabetes but their role in the remission and progr...
Type 2 diabetes subtypes for precision medicine: methodological challenges and alternative prediction-based approaches
Type 2 diabetes subtypes for precision medicine: methodological challenges and alternative prediction-based approaches
Growing interest in precision diagnostics has stimulated efforts to classify type 2 diabetes into more granular subtypes. ...
Ele Ferrannini, 1948–2026
Ele Ferrannini, 1948–2026
The diabetes community has lost a giant. Professor Ele Ferrannini passed away on 23 ...
Effects of time-restricted eating on markers of glucose metabolism and regulation in individuals with prediabetes or type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials
Effects of time-restricted eating on markers of glucose metabolism and regulation in individuals with prediabetes or type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials
This systematic review and meta-analysis aimed to investigate the effects of time-restricted eating (TRE) on glucose metab...
A narrative systematic review of definitions and diagnostic criteria for disordered eating and eating disorders in type 1 diabetes
A narrative systematic review of definitions and diagnostic criteria for disordered eating and eating disorders in type 1 diabetes
Type 1 diabetes and disordered eating (T1DE) affects 8–37.1% of adults and is associated with high rates of morbidit...
Understanding MASLD and diabetes through lived experience
Understanding MASLD and diabetes through lived experience
Acknowledgements E. Yat-man Lui (Department of Medicine and Therapeutics, The Ch...
Cardiac autonomic neuropathy predicts renal decline in type 1 diabetes mellitus: a 15 year follow-up study
Cardiac autonomic neuropathy predicts renal decline in type 1 diabetes mellitus: a 15 year follow-up study
The aim of this study was to determine whether cardiac autonomic neuropathy (CAN) is an independent risk factor for kidney...
Is MASLD an independent risk factor for micro- and macrovascular complications of diabetes? A critical reappraisal and future directions
Is MASLD an independent risk factor for micro- and macrovascular complications of diabetes? A critical reappraisal and future directions
Recent awareness that metabolic dysfunction-associated steatotic liver disease (MASLD) is a common liver condition in indi...
Metabolic implications of hepatic, pancreatic and abdominal adipose tissue depots in Asian Indians across normoglycaemia, prediabetes and type 2 diabetes
Metabolic implications of hepatic, pancreatic and abdominal adipose tissue depots in Asian Indians across normoglycaemia, prediabetes and type 2 diabetes
The aim of this study was to evaluate hepatic, pancreatic and abdominal fat depots across glycaemic categories in Asian In...
Incidence and independent risk factors for heart failure in a population-based cohort of 19,892 individuals with newly diagnosed diabetes
Incidence and independent risk factors for heart failure in a population-based cohort of 19,892 individuals with newly diagnosed diabetes
Heart failure (HF) is a common complication of diabetes, associated with a high mortality rate and a substantial healthcar...
Metformin protects podocytes by inhibiting the MAPK14–SLC7A11–GPX4 axis and dysregulation of fatty acid metabolism
Metformin protects podocytes by inhibiting the MAPK14–SLC7A11–GPX4 axis and dysregulation of fatty acid metabolism
Diabetic nephropathy is a leading cause of end-stage renal disease, with podocyte loss being a critical event in its progr...
Predicting future risk of type 1 and type 2 diabetes after gestational diabetes mellitus using polygenic scores: a cohort study
Predicting future risk of type 1 and type 2 diabetes after gestational diabetes mellitus using polygenic scores: a cohort study
Women with previous gestational diabetes mellitus (GDM) have an increased risk of developing both type 1 and type 2 diabet...
Concurrent training is associated with enhanced post-exercise ceramide clearance and fat oxidation capacity in individuals with type 2 diabetes following lifestyle intervention
Concurrent training is associated with enhanced post-exercise ceramide clearance and fat oxidation capacity in individuals with type 2 diabetes following lifestyle intervention
This study aimed to investigate whether concurrent training, when added to a palaeolithic-type diet-induced weight loss in...
Endometriosis subtypes and risk of type 2 diabetes: the Advancing Research on Cardiovascular Health and Endometriosis Study (ARCHES) retrospective cohort study
Endometriosis subtypes and risk of type 2 diabetes: the Advancing Research on Cardiovascular Health and Endometriosis Study (ARCHES) retrospective cohort study
Endometriosis is a heterogeneous inflammatory condition that may influence long-term metabolic health. Prior studies have ...
Screening and diagnosis of liver disease in diabetes: a guide and evidence-based assessment
Screening and diagnosis of liver disease in diabetes: a guide and evidence-based assessment
Most people with type 2 diabetes have metabolic dysfunction-associated steatotic liver disease (MASLD), yet fewer than 2% ...
A GLP-1 receptor agonist enhances islet microvascular flow through nitric oxide-dependent mechanisms in a diabetic mouse model: investigation using intravital two-photon imaging
A GLP-1 receptor agonist enhances islet microvascular flow through nitric oxide-dependent mechanisms in a diabetic mouse model: investigation using intravital two-photon imaging
Impaired regulation of islet microvascular blood flow has been implicated in beta cell dysfunction in diabetes; this dysre...
High prevalence of low faecal elastase levels in individuals with type 1 diabetes is associated with diabetes duration but not with marked alterations in food intake or clinical symptoms
High prevalence of low faecal elastase levels in individuals with type 1 diabetes is associated with diabetes duration but not with marked alterations in food intake or clinical symptoms
Although exocrine pancreatic insufficiency (EPI) is thought to be common in type 1 diabetes, little is known about the rel...
LECT2–RPS27A interaction involving Lys48 attenuates neuroinflammation in diabetic retinopathy
LECT2–RPS27A interaction involving Lys48 attenuates neuroinflammation in diabetic retinopathy
Leukocyte cell-derived chemotaxin 2 (LECT2), a newly discovered hepatokine involved in immunomodulation and inflammatory p...
Declining FXR expression coordinates neonatal beta cell mass development with microbial bile acid metabolism maturation in mice
Declining FXR expression coordinates neonatal beta cell mass development with microbial bile acid metabolism maturation in mice
Diet switch during weaning induces gut microbiome maturation, accompanied by the formation of adequate functional beta cel...
LDHA induces beta cell dedifferentiation in diabetes through metabolic and epigenetic reprogramming
LDHA induces beta cell dedifferentiation in diabetes through metabolic and epigenetic reprogramming
Pancreatic beta cell dedifferentiation underlies the reversible reduction in beta cell mass and function in diabetes. Expl...
Evolution of islet autoantibodies in the Environmental Determinants of Islet Autoimmunity (ENDIA) prospective cohort
Evolution of islet autoantibodies in the Environmental Determinants of Islet Autoimmunity (ENDIA) prospective cohort
Islet autoantibodies herald early type 1 diabetes. However, less is known of the evolution of autoantibodies to the islet ...
Superiority of 1 h plasma glucose vs fasting plasma glucose, 2 h plasma glucose and HbA for the diagnosis of type 2 diabetes
Superiority of 1 h plasma glucose vs fasting plasma glucose, 2 h plasma glucose and HbA for the diagnosis of type 2 diabetes
The IDF has proposed 1 h plasma glucose (1 h PG) as a diagnostic test for type 2 diabetes. This study evaluated the utilit...
Inter- and intra-physician variability in insulin injection adjustments compared with Bayesian algorithm recommendations in type 1 diabetes
Inter- and intra-physician variability in insulin injection adjustments compared with Bayesian algorithm recommendations in type 1 diabetes
There is an unmet need for automated insulin adjustments for multiple daily injections in type 1 diabetes under unsupervis...
α7 Nicotinic acetylcholine receptor activation rescues mitochondrial dysfunction in gestational diabetes mellitus by competing with p66Shc for VDAC1 binding
α7 Nicotinic acetylcholine receptor activation rescues mitochondrial dysfunction in gestational diabetes mellitus by competing with p66Shc for VDAC1 binding
Gestational diabetes mellitus (GDM) is associated with placental hormone-induced insulin resistance; however, the mechanis...
Diabetogenic processes for insulin resistance-linked hyperinsulinaemia are associated with colorectal cancer
Diabetogenic processes for insulin resistance-linked hyperinsulinaemia are associated with colorectal cancer
Type 2 diabetes has been associated with increased risk of colorectal cancer (CRC), but the specific diabetogenic pathways...
Impact of overweight and obesity on fasting insulin secretion in men and women without diabetes: effect sizes and mechanisms
Impact of overweight and obesity on fasting insulin secretion in men and women without diabetes: effect sizes and mechanisms
Fasting hyperinsulinaemia is a key feature of obesity and is implicated in diabetes progression. However, the following as...
Dietary intake of vitamins A, B, C, D and E and risk of islet autoimmunity and type 1 diabetes in genetically at-risk children: a prospective study from the DIPP birth cohort
Dietary intake of vitamins A, B, C, D and E and risk of islet autoimmunity and type 1 diabetes in genetically at-risk children: a prospective study from the DIPP birth cohort
In this prospective birth cohort study, we examined whether the dietary intake of A, B, C, D and E vitamins is associated ...
Effects of combined intraduodenal administration of lauric acid and -tryptophan on postprandial plasma glucose, glucoregulatory hormones and gastric emptying in type 2 diabetes: a double-blind, randomised, crossover study
Effects of combined intraduodenal administration of lauric acid and -tryptophan on postprandial plasma glucose, glucoregulatory hormones and gastric emptying in type 2 diabetes: a double-blind, randomised, crossover study
In healthy men, lauric acid (C12) and l-tryptophan (Trp), when administered intraduodenally in loads of 1.26 and 0.42 kJ/m...
Efficacy of tirzepatide versus semaglutide in achieving therapeutic targets in type 2 diabetes: a post hoc analysis of the SURPASS-2 Trial
Efficacy of tirzepatide versus semaglutide in achieving therapeutic targets in type 2 diabetes: a post hoc analysis of the SURPASS-2 Trial
Simultaneous control of HbA1c, lipid profile, BP and body weight is essential for preventing chronic complications of type...
Load More
format_indent_increase