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Integrated Evidence from VigiBase and Clinical Trials: A Comprehensive Pharmacovigilance Analysis of Seven Glucagon-Like Peptide 1 Receptor Agonists (GLP-1 RAs)
Integrated Evidence from VigiBase and Clinical Trials: A Comprehensive Pharmacovigilance Analysis of Seven Glucagon-Like Peptide 1 Receptor Agonists (GLP-1 RAs)
Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are key therapies for type 2 diabetes and...
Impact of SGLT2 Inhibitors on Clinical Outcomes in Patients with Diabetes Mellitus Following Heart Transplantation: A Meta-analysis
Impact of SGLT2 Inhibitors on Clinical Outcomes in Patients with Diabetes Mellitus Following Heart Transplantation: A Meta-analysis
In this new era, heart transplantation (HT) is rapidly gaining popularity worldwide. Patients with end-stage heart disease...
Persistence-Dependent Effectiveness of Tirzepatide on the Cardio-Metabolic-Kidney Syndrome Outcomes in Obesity: Real-World Evidence from the United Arab Emirates
Persistence-Dependent Effectiveness of Tirzepatide on the Cardio-Metabolic-Kidney Syndrome Outcomes in Obesity: Real-World Evidence from the United Arab Emirates
Tirzepatide has been associated with significant reductions in body weight in randomized clinical trials. However, real-wo...
Blood Glucose Monitoring Expert Group and Best Practice Recommendation—FITTER BiG
Blood Glucose Monitoring Expert Group and Best Practice Recommendation—FITTER BiG
Diabetes mellitus presents a growing public health challenge across geographies including Asia, particularly in countries ...
Semaglutide and Cardiovascular Outcomes in People with Type 2 Diabetes: A SUSTAIN-6 Post Hoc Analysis by Weight Loss Category
Semaglutide and Cardiovascular Outcomes in People with Type 2 Diabetes: A SUSTAIN-6 Post Hoc Analysis by Weight Loss Category
Type 2 diabetes (T2D) is a known risk factor for cardiovascular (CV) disease. Glucagon-like peptide-1 receptor agonists (G...
Morbidity and Mortality Rates in People with Diabetes Mellitus With an Active Charcot's Neuro-Osteoarthropathy: A 15-Year Single-Center Retrospective Analysis
Morbidity and Mortality Rates in People with Diabetes Mellitus With an Active Charcot's Neuro-Osteoarthropathy: A 15-Year Single-Center Retrospective Analysis
Diabetes related Charcot neuro-osteoarthropathy (CN) of the foot is associated with increased risks of amputation and prem...
Association Between Anthropometric Indices and Presence of Type 2 Diabetes Mellitus in Obesity
Association Between Anthropometric Indices and Presence of Type 2 Diabetes Mellitus in Obesity
Obesity and type 2 diabetes mellitus (T2DM) are global challenges, with obesity increasing risk of T2DM. Body mas...
Efficacy and Safety of Insulin Efsitora Versus Degludec in Adults with Type 2 Diabetes Who Are Insulin-Naïve: Japan Subgroup Analysis of QWINT-2
Efficacy and Safety of Insulin Efsitora Versus Degludec in Adults with Type 2 Diabetes Who Are Insulin-Naïve: Japan Subgroup Analysis of QWINT-2
The phase 3 QWINT-2 study demonstrated that once-weekly insulin efsitora alfa (efsitora) was noninferior to once-daily ins...
Treatment Options for Patients with Maturity-Onset Diabetes of the Young (MODY): A Systematic Review of Literature: 2026 Update
Treatment Options for Patients with Maturity-Onset Diabetes of the Young (MODY): A Systematic Review of Literature: 2026 Update
Maturity-onset diabetes of the young (MODY) is a rare monogenic form of diabetes characterized by impaired insulin secreti...
Overlap of Gestational Diabetes Mellitus and Pre-eclampsia: A Scoping Review
Overlap of Gestational Diabetes Mellitus and Pre-eclampsia: A Scoping Review
Gestational diabetes mellitus (GDM) and preeclampsia (PE) are among the most common medical complications in pregnancy, wi...
Novel Clinical and Pre-clinical Obesity Estimates in Older Indian Adults: Insights from a Nationally Representative Dataset
Novel Clinical and Pre-clinical Obesity Estimates in Older Indian Adults: Insights from a Nationally Representative Dataset
Obesity is a multifactorial condition that is not well captured by conventional anthropometry. Emerging frameworks, includ...
Risk of Progression and Costs of Care for Patients with Type 2 Diabetes and Chronic Kidney Disease
Risk of Progression and Costs of Care for Patients with Type 2 Diabetes and Chronic Kidney Disease
Chronic kidney disease (CKD) progression is associated with a significant incremental economic burden. Previous work has d...
A Pragmatic Approach to Improving Management and Patient Flow for Painful Diabetic Neuropathy in UK Primary Care
A Pragmatic Approach to Improving Management and Patient Flow for Painful Diabetic Neuropathy in UK Primary Care
Painful diabetic peripheral neuropathy (pDPN) affects approximately 25% of individuals with diabetes in the UK and remains...
The Mechanisms of Inflammatory Factors and the Total Load of Cerebral Small Vessel Disease in Diabetic Retinopathy and Cognitive Impairment
The Mechanisms of Inflammatory Factors and the Total Load of Cerebral Small Vessel Disease in Diabetic Retinopathy and Cognitive Impairment
The purpose of this study was to explore the roles and methods of inflammatory factors and total load of cerebral small ve...
Effect of Automated Insulin Delivery System Therapy at Diagnosis on Metabolic Control in Children and Adolescents with Type 1 Diabetes
Effect of Automated Insulin Delivery System Therapy at Diagnosis on Metabolic Control in Children and Adolescents with Type 1 Diabetes
The primary goal of managing type 1 diabetes mellitus (T1D) is to achieve glycemic control and prevent both acute...
Pharmacokinetic Characteristics of a Once-Weekly Combination Therapy of Insulin Icodec and Semaglutide Versus Its Separate Components in Chinese Individuals with Type 2 Diabetes
Pharmacokinetic Characteristics of a Once-Weekly Combination Therapy of Insulin Icodec and Semaglutide Versus Its Separate Components in Chinese Individuals with Type 2 Diabetes
IcoSema is under development as a once-weekly injectable combination therapy of icodec (basal insulin) and semaglutide (gl...
Efficacy and Safety of Once-Weekly Insulin Icodec in Indian Participants with Diabetes: Results from ONWARDS 1, 4, and 6 Studies
Efficacy and Safety of Once-Weekly Insulin Icodec in Indian Participants with Diabetes: Results from ONWARDS 1, 4, and 6 Studies
These analyses explored the efficacy and safety of once-weekly insulin icodec (icodec) in Indian participants with type&am...
Real-World Effectiveness of Tirzepatide versus Semaglutide on HbA1c and Weight in Patients with Type 2 Diabetes
Real-World Effectiveness of Tirzepatide versus Semaglutide on HbA1c and Weight in Patients with Type 2 Diabetes
To evaluate real-world hemoglobin A1c (HbA1c) and weight change in adults initiating treatment with tirzepatide (dual gluc...
A Multicenter, Prospective, Observational, and Single-Arm Interventional Study of Mirogabalin in Diabetic Peripheral Neuropathic Pain: Rationale and Design of Dia-NeP
A Multicenter, Prospective, Observational, and Single-Arm Interventional Study of Mirogabalin in Diabetic Peripheral Neuropathic Pain: Rationale and Design of Dia-NeP
The exact prevalence of and recent changes in diabetic polyneuropathy (DPN) and diabetic peripheral neuropathic pain (DPNP...
Tubeless Insulin Pump Combined with a Cloud-Based Data Management Platform: Real-World Evidence from 14,765 French People with Diabetes
Tubeless Insulin Pump Combined with a Cloud-Based Data Management Platform: Real-World Evidence from 14,765 French People with Diabetes
This study aimed to examine glucose metrics and insulin delivery patterns in children, adolescents, and adults with type&a...
Identifying the Healthcare Burden of Diabetic Ketoacidosis: Economic Analysis and Mitigation Strategies for Adult Patients in the United Arab Emirates
Identifying the Healthcare Burden of Diabetic Ketoacidosis: Economic Analysis and Mitigation Strategies for Adult Patients in the United Arab Emirates
Diabetic ketoacidosis (DKA) is a potentially fatal diabetes complication marked by hyperglycemia, ketonemia, and acidosis ...
Protective Role of Serum β-Hydroxybutyrate in Early Diabetic Kidney Disease: A Longitudinal Study
Protective Role of Serum β-Hydroxybutyrate in Early Diabetic Kidney Disease: A Longitudinal Study
β-Hydroxybutyrate (βHB), the most stable form of ketone bodies, has exhibited protective effects in metabolic an...
Insights into the Mechanism of Action of Tirzepatide: A Narrative Review
Insights into the Mechanism of Action of Tirzepatide: A Narrative Review
Tirzepatide is the first dual long-acting glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-...
Diabetes Educators: Understanding the Role of Finerenone in Chronic Kidney Disease Associated with Type 2 Diabetes Mellitus
Diabetes Educators: Understanding the Role of Finerenone in Chronic Kidney Disease Associated with Type 2 Diabetes Mellitus
People living with type 2 diabetes mellitus (T2DM) are at risk of developing diabetes-related complications such as chroni...
A Randomized Phase 3 Study Evaluating the Efficacy and Safety of Alogliptin in Pediatric Participants with Type 2 Diabetes Mellitus
A Randomized Phase 3 Study Evaluating the Efficacy and Safety of Alogliptin in Pediatric Participants with Type 2 Diabetes Mellitus
There is an unmet need for pharmacological therapies for children with type 2 diabetes mellitus (T2DM). We assessed the ef...
Advances in Imaging Techniques for Assessing Myocardial Microcirculation in People with Diabetes
Advances in Imaging Techniques for Assessing Myocardial Microcirculation in People with Diabetes
Microangiopathy is a key complication of diabetes, adversely effecting several organs including the heart, kidneys, eyes, ...
The Prevalence of Atherosclerotic Cardiovascular Disease in Patients with Type 2 Diabetes in Jordan: The PACT-MEA Study
The Prevalence of Atherosclerotic Cardiovascular Disease in Patients with Type 2 Diabetes in Jordan: The PACT-MEA Study
This study investigated the prevalence and clinical management of atherosclerotic cardiovascular disease (ASCVD) and ASCVD...
Knowledge, Attitudes, and Practices in Neonatal Diabetes Mellitus Management: the JEnious-NeOnatal-DIabetes (JENODI) Survey
Knowledge, Attitudes, and Practices in Neonatal Diabetes Mellitus Management: the JEnious-NeOnatal-DIabetes (JENODI) Survey
We aimed to explore the knowledge, attitude, and management of neonatal diabetes mellitus (NDM) among members of the Inter...
Predictors of Composite Maternal and Fetal Outcomes among Pregnant Women with Early-Onset Type 2 Diabetes: A Cross-Sectional Study
Predictors of Composite Maternal and Fetal Outcomes among Pregnant Women with Early-Onset Type 2 Diabetes: A Cross-Sectional Study
The most common form of pregestational diabetes in pregnancy is type 2 diabetes, requiring strict metabolic monitoring owi...
Clinical Profile and Treatment Patterns in Individuals with Type 2 Diabetes and Chronic Kidney Disease Who Initiate a GLP-1 Receptor Agonist: A Multinational Cohort Study
Clinical Profile and Treatment Patterns in Individuals with Type 2 Diabetes and Chronic Kidney Disease Who Initiate a GLP-1 Receptor Agonist: A Multinational Cohort Study
Novel therapies are emerging for the prevention of chronic kidney disease (CKD) progression in patients with type 2 diabet...
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