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Immunological Drug–Drug Interactions in Immune Checkpoint Inhibitor Therapy: Mechanisms, Clinical Evidence, and Artificial Intelligence
Immunological Drug–Drug Interactions in Immune Checkpoint Inhibitor Therapy: Mechanisms, Clinical Evidence, and Artificial Intelligence
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, producing durable responses across multiple malignanc...
Mind-Body Therapies for Depression and Anxiety Symptoms in People with Cancer: A Systematic Review with Network Meta-Analysis
Mind-Body Therapies for Depression and Anxiety Symptoms in People with Cancer: A Systematic Review with Network Meta-Analysis
Mind-body therapies (MBTs) are promising forms of treatment for depression and anxiety symptoms in people with cancer, how...
Preventive and Therapeutic Interventions for Anticancer Drug-induced Dermatologic Toxicities: a Scoping Review
Preventive and Therapeutic Interventions for Anticancer Drug-induced Dermatologic Toxicities: a Scoping Review
Anticancer drug-induced dermatologic toxicities frequently compromise quality of life and treatment adherence. While diver...
Impact of 18-FDG PET/CT on Multidisciplinary Decision-Making and Management in Abdominal Malignancies: A Systematic Review and Meta-Analysis
Impact of 18-FDG PET/CT on Multidisciplinary Decision-Making and Management in Abdominal Malignancies: A Systematic Review and Meta-Analysis
To systematically review and assess the impact of 18 F-FDG PET/CT on multidisciplinary team (MDT) decision-making...
Targeting GD2 with CAR-T Cell Therapy in Neuroblastoma: Updates, Challenges, and Future Perspectives
Targeting GD2 with CAR-T Cell Therapy in Neuroblastoma: Updates, Challenges, and Future Perspectives
High-risk neuroblastoma remains a challenging pediatric cancer, with survival rates lagging despite advances in multimodal...
Advancing Systemic Treatment beyond First Line for Advanced Hepatocellular Carcinoma
Advancing Systemic Treatment beyond First Line for Advanced Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) ranks among the most prevalent solid malignancies worldwide. A substantial proportion of pa...
Microbiome in Gastrointestinal Tumors: Implications in Oncogenesis and Therapeutic Response
Microbiome in Gastrointestinal Tumors: Implications in Oncogenesis and Therapeutic Response
To provide an updated overview of the role of the human microbiome in the initiation, progression, and therapeutic respons...
Liquid Biopsy in Modern Oncology: Advances, Challenges, and Future Perspectives in Early Cancer Detection, Minimal Residual Disease, and Dynamic Patient Monitoring
Liquid Biopsy in Modern Oncology: Advances, Challenges, and Future Perspectives in Early Cancer Detection, Minimal Residual Disease, and Dynamic Patient Monitoring
Liquid biopsy has emerged as a minimally invasive approach to overcome the limitations of tissue biopsy in oncology. This ...
Regimen-Related Oral Mucosal Injury: Pathobiology, Clinical Consequences and Rationale for Intervention Across Cancer Treatment Modalities
Regimen-Related Oral Mucosal Injury: Pathobiology, Clinical Consequences and Rationale for Intervention Across Cancer Treatment Modalities
Mucosal injury of the alimentary tract (mucositis) has been a consistent, markedly symptomatic, and clinically disruptive ...
Plant-Derived Diterpenoids as Potential Chemotherapeutics for Gastric Cancer
Plant-Derived Diterpenoids as Potential Chemotherapeutics for Gastric Cancer
Gastric cancer remains a leading contributor to cancer-related mortality worldwide despite its declining incidence, with p...
Decoding the 2023 FIGO Staging System in Endometrial Cancer: A Practical, Visually Guided Framework for Molecular Risk-Adapted Care Incorporating the 2025 Risk Group Update
Decoding the 2023 FIGO Staging System in Endometrial Cancer: A Practical, Visually Guided Framework for Molecular Risk-Adapted Care Incorporating the 2025 Risk Group Update
The FIGO staging system for endometrial cancer has evolved substantially over the past five decades, progressing from the ...
PARP Inhibitors as Radiosensitizers: Current Evidence and Future Directions
PARP Inhibitors as Radiosensitizers: Current Evidence and Future Directions
Radiotherapy remains a fundamental pillar of cancer treatment, however its efficacy is still often limited by tumor radior...
Decoding Occult Cervical Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma: From AI-Driven Multimodal Fusion to Clinical Translation
Decoding Occult Cervical Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma: From AI-Driven Multimodal Fusion to Clinical Translation
This review examines the limitations of conventional macroscopic approaches in detecting occult cervical lymph node metast...
The Role of EZH2 in Malignant Pleural Mesothelioma and Beyond: Current Practice and Future Perspectives
The Role of EZH2 in Malignant Pleural Mesothelioma and Beyond: Current Practice and Future Perspectives
Malignant pleural mesothelioma (MPM) remains a rare but highly aggressive malignancy with limited treatment options and po...
Current Understanding of CHIP’s Immunobiological Footprint with A Focus on Gastrointestinal Disorders: A Review of the Literature
Current Understanding of CHIP’s Immunobiological Footprint with A Focus on Gastrointestinal Disorders: A Review of the Literature
Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by the age-associated expansion of hematopoietic s...
Clusterin in Head and Neck Squamous Cell Carcinoma: Diagnostic, Prognostic, and Therapeutic Implications
Clusterin in Head and Neck Squamous Cell Carcinoma: Diagnostic, Prognostic, and Therapeutic Implications
Head and neck squamous cell carcinoma (HNSCC) is a global malignancy characterised by extremely low survival rates, primar...
Sacituzumab Tirumotecan Across Gynecologic Malignancies: One Target, Multiple Diseases
Sacituzumab Tirumotecan Across Gynecologic Malignancies: One Target, Multiple Diseases
Sacizuzumab Tirumotecan is a novel antibody-drug conjugate targeting TROP2 glycoprotein, which is highly expressed across ...
Correction to: Postmastectomy Functional Impairments
Correction to: Postmastectomy Functional Impairments
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Integrative Approaches in the Treatment of Patients Affected by Lymphoma
Integrative Approaches in the Treatment of Patients Affected by Lymphoma
Lymphoma is the most frequent hematological malignancy with wide disease spectrum of watchful waiting period, active treat...
Shifting Strategies in the Treatment of Pediatric Craniopharyngioma
Shifting Strategies in the Treatment of Pediatric Craniopharyngioma
Craniopharyngiomas represent one of the most challenging diseases to treat. Despite their benign histology, and after many...
Genomic Landscape of Pleural Mesothelioma and Therapeutic Aftermaths
Genomic Landscape of Pleural Mesothelioma and Therapeutic Aftermaths
In this article, we provide a comprehensive analysis of recent progress in the genetic characterisation of pleural mesothe...
Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives
Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives
This review summarizes current findings regarding limb amputation within the context of cancer, especially in osteosarcoma...
Postmastectomy Functional Impairments
Postmastectomy Functional Impairments
This narrative review aims to offer a thorough summary of functional impairments commonly encountered by breast cancer sur...
Immune Priming with Spatially Fractionated Radiation Therapy
Immune Priming with Spatially Fractionated Radiation Therapy
This review aims to summarize the current preclinical and clinical evidence of nontargeted immune effects of spatially fra...
Advances in Treatment of Waldenström Macroglobulinemia
Advances in Treatment of Waldenström Macroglobulinemia
The discovery of recurring somatic mutations, in particular MYD88 and CXCR4 mutations, in Waldenström macroglobulinem...
What Is New in Cutaneous T Cell Lymphoma?
What Is New in Cutaneous T Cell Lymphoma?
This review focuses on updates in prognosis, pathogenesis, and treatment of cutaneous T cell lymphoma (CTCL). Cohort studi...
Prostate Cancer in Transgender Women: Epidemiology, Clinical Characteristics, and Management Challenges
Prostate Cancer in Transgender Women: Epidemiology, Clinical Characteristics, and Management Challenges
To systematically review the evidence on prostate cancer (PCa) in transgender women (TGW). A total of 25 studies were incl...
Navigating the Rapidly Evolving Advanced Urothelial Carcinoma Treatment Landscape: Insights from Italian Experts
Navigating the Rapidly Evolving Advanced Urothelial Carcinoma Treatment Landscape: Insights from Italian Experts
To discuss recent advances in the treatment of advanced urothelial carcinoma (UC) and how best to incorporate new therapie...
Evolving Role of CAR T Cell Therapy in First- and Second-Line Treatment of Large B Cell Lymphoma
Evolving Role of CAR T Cell Therapy in First- and Second-Line Treatment of Large B Cell Lymphoma
We review the recent practice-changing trials of anti-CD19 chimeric antigen receptor (CAR) T cell therapies in large B cel...
Advances in the Management of Recurrent Cervical Cancer: State of the Art and Future Perspectives
Advances in the Management of Recurrent Cervical Cancer: State of the Art and Future Perspectives
This review aims to give an insight into the currently available options for recurrent/metastatic (R/M) cervical cancer (C...
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