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Beyond CDK4/6 Inhibition: Current Strategies in Hormone Receptor-Positive Metastatic Breast Cancer
Beyond CDK4/6 Inhibition: Current Strategies in Hormone Receptor-Positive Metastatic Breast Cancer
We focus our second-line treatment strategy on biomarker-defined resistance mechanisms that emerge after progression on CD...
Advances in Pharmacologic- and Non-pharmacologic Interventions for Cancer Pain: A Narrative Review
Advances in Pharmacologic- and Non-pharmacologic Interventions for Cancer Pain: A Narrative Review
Cancer pain is common, heterogeneous, and multidimensional. The management of cancer pain is evolving toward a personalize...
Systemic Therapy for Solitary Fibrous Tumor
Systemic Therapy for Solitary Fibrous Tumor
Solitary fibrous tumor (SFT) is an exceedingly rare mesenchymal neoplasm classified as a soft tissue sarcoma (STS). While ...
Breakthroughs in HBV-related HCC Therapy: The Unmatched Potential of Immune Checkpoint Inhibitors
Breakthroughs in HBV-related HCC Therapy: The Unmatched Potential of Immune Checkpoint Inhibitors
Immune checkpoint inhibitors have reshaped the therapeutic landscape of hepatocellular carcinoma by restoring T cell–...
Emerging Applications of CAR-T Cell Therapy in Overcoming Resistance and Expanding Targets in Hematologic Malignancies: Insights from Recent Research
Emerging Applications of CAR-T Cell Therapy in Overcoming Resistance and Expanding Targets in Hematologic Malignancies: Insights from Recent Research
Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment outcomes of patients with hematologic ma...
Oncofertility in the Age of HER2 Blockade, Immunotherapy, PARP inhibitors, CDK4/6 inhibitors and Endocrine Treatment: Unanswered Questions in Breast Cancer
Oncofertility in the Age of HER2 Blockade, Immunotherapy, PARP inhibitors, CDK4/6 inhibitors and Endocrine Treatment: Unanswered Questions in Breast Cancer
As survival among reproductive-age patients with breast cancer continues to improve with modern therapies, concerns regard...
The Immunological Landscape of the Tumor Microenvironment: Implications for Immunotherapy of Unresectable and Metastatic Soft Tissue Sarcomas
The Immunological Landscape of the Tumor Microenvironment: Implications for Immunotherapy of Unresectable and Metastatic Soft Tissue Sarcomas
The field of immunotherapy for unresectable soft tissue sarcomas (STS) is transitioning from a one-size-fits-all approach ...
Recent Advances in Neoadjuvant Treatment of Anaplastic Thyroid Carcinoma: A Narrative Review
Recent Advances in Neoadjuvant Treatment of Anaplastic Thyroid Carcinoma: A Narrative Review
Anaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy characterized by rapid progression, restricted therap...
Advances in Immunotherapy for Breast Cancer: Up-to-date Strategies of Immune Checkpoint Inhibitors and Therapeutic Vaccines
Advances in Immunotherapy for Breast Cancer: Up-to-date Strategies of Immune Checkpoint Inhibitors and Therapeutic Vaccines
Breast cancer remains one of the leading causes of cancer-related mortality among women worldwide. Although advances in ea...
Interaction between Regulated Cell Death Pathways and Core Cellular Processes: Unraveling the Molecular Mechanisms of Cardiotoxicity of Antitumor Drugs
Interaction between Regulated Cell Death Pathways and Core Cellular Processes: Unraveling the Molecular Mechanisms of Cardiotoxicity of Antitumor Drugs
With improved cancer survival, cancer therapy-related cardiovascular toxicity has emerged as a major non-cancer cause of m...
Cardiotoxicity of Targeted Therapies in Hematologic Malignancies: From Molecular Mechanisms to Clinical Management
Cardiotoxicity of Targeted Therapies in Hematologic Malignancies: From Molecular Mechanisms to Clinical Management
The therapeutic landscape of hematologic malignancies has been transformed over the past decade by the shift from conventi...
Current Treatment Options for Adult Grade 2 IDH-mutant Diffuse Gliomas in the Vorasidenib Era: Patient Selection, Sequencing, and Practical Management
Current Treatment Options for Adult Grade 2 IDH-mutant Diffuse Gliomas in the Vorasidenib Era: Patient Selection, Sequencing, and Practical Management
Management of adult WHO CNS grade 2 IDH-mutant diffuse gliomas has entered a more precise postoperative era. Vorasidenib h...
Role of Troponins in CardioOncology
Role of Troponins in CardioOncology
Troponins are an integral part of the diagnosis of acute coronary syndromes in cardiology. It is also useful in many other...
Current Treatment Options and Emerging Technologies for Pelvic Bone Tumors: From Limb Salvage to Precision Oncology
Current Treatment Options and Emerging Technologies for Pelvic Bone Tumors: From Limb Salvage to Precision Oncology
In our practice, the treatment of pelvic bone tumors should begin with a multidisciplinary sarcoma-board evaluation that i...
Current status of Complementary and Alternative Medicine Interventions in the Management of Pancreatic Cancer – An Overview
Current status of Complementary and Alternative Medicine Interventions in the Management of Pancreatic Cancer – An Overview
Pancreatic cancer (PC) remains the deadliest cancer worldwide. Most patients are diagnosed at the advanced or metastatic s...
Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: Clinical Relevance, Impact on Outcome, Preventive Measures and Treatment Strategies
Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: Clinical Relevance, Impact on Outcome, Preventive Measures and Treatment Strategies
The introduction of TKIs into the therapeutic armamentarium of CML has changed the disease paradigm, increasing long-term ...
The Quest for Circulating Biomarkers in Neuroendocrine Neoplasms: a Clinical Perspective
The Quest for Circulating Biomarkers in Neuroendocrine Neoplasms: a Clinical Perspective
Given the considerable heterogeneity in neuroendocrine neoplasms (NENs), it appears unlikely that a sole biomarker exists ...
Updates in Management of Malignant Pleural Mesothelioma
Updates in Management of Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) is an aggressive asbestos-associated thoracic malignancy that is usually incurable. A...
The Evolving Treatment Landscape of Medullary Thyroid Cancer
The Evolving Treatment Landscape of Medullary Thyroid Cancer
Genetic assessment is crucial to address the correct treatment for advanced medullary thyroid cancer (MTC). Multi tyrosine...
Application of Engineered Dendritic Cell Vaccines in Cancer Immunotherapy: Challenges and Opportunities
Application of Engineered Dendritic Cell Vaccines in Cancer Immunotherapy: Challenges and Opportunities
The primary objective of this study is to evaluate the effectiveness of cancer vaccines containing genetically modified de...
Selecting Optimal First-Line Treatment for Microsatellite Stable and Non-Mutated RAS/BRAF Metastatic Colorectal Cancer
Selecting Optimal First-Line Treatment for Microsatellite Stable and Non-Mutated RAS/BRAF Metastatic Colorectal Cancer
Standard frontline treatment of metastatic colorectal cancer (CRC) is cytotoxic chemotherapy plus a biologic agent such as...
Anti-HER2 Drugs for the Treatment of Advanced HER2 Positive Breast Cancer
Anti-HER2 Drugs for the Treatment of Advanced HER2 Positive Breast Cancer
Approximately 15–20% of breast cancers (BC) demonstrate HER2 overexpression/gene amplification. Historically, before...
Update of Diagnosis and Targeted Therapy for ALK+ Inflammation Myofibroblastic Tumor
Update of Diagnosis and Targeted Therapy for ALK+ Inflammation Myofibroblastic Tumor
Inflammatory myofibroblastic tumor (IMT), characterized by intermediate malignancy and a propensity for recurrence, has pr...
Frontiers of Ovarian Carcinosarcoma
Frontiers of Ovarian Carcinosarcoma
Ovarian carcinosarcoma (OCS), also known as a malignant mixed Müllerian tumour (MMMT), is a rare and aggressive form ...
The Role of Liver Transplantation in the Treatment of Liver Metastases from Neuroendocrine Tumors
The Role of Liver Transplantation in the Treatment of Liver Metastases from Neuroendocrine Tumors
Transplant oncology is a new field of medicine referred to the use of solid organ transplantation, particularly the liver,...
Developing Strategies to Improve the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia
Developing Strategies to Improve the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a fatal blood malignancy. With the development of immunotherapy, particularly chimeric ant...
Systemic Therapy in Advanced Pleomorphic Liposarcoma: a Comprehensive Review
Systemic Therapy in Advanced Pleomorphic Liposarcoma: a Comprehensive Review
The therapeutic approach of pleomorphic liposarcoma (PLPS), a rare high-grade subgroup of soft tissue sarcoma, is commonly...
Sequencing Systemic Therapy in Hepatocellular Carcinoma
Sequencing Systemic Therapy in Hepatocellular Carcinoma
Multiple treatment options are now approved for unresectable hepatocellular carcinoma (HCC). An immune checkpoint inhibito...
Correction to: Update on Immunotherapy Cardiotoxicity: Checkpoint Inhibitors, CAR T, and Beyond
Correction to: Update on Immunotherapy Cardiotoxicity: Checkpoint Inhibitors, CAR T, and Beyond
Cite this articlePatel, M., Hudson, O., Han, J. et al. Correction to: Update on Immunotherapy Cardiotoxicity: Checkpoint I...
Optimal Therapeutic Strategy for PD-L1 Negative Metastatic Non-Small Cell Lung Cancer: A Decision-Making Guide Based on Clinicopathological and Molecular Features
Optimal Therapeutic Strategy for PD-L1 Negative Metastatic Non-Small Cell Lung Cancer: A Decision-Making Guide Based on Clinicopathological and Molecular Features
Strategies using immune checkpoint inhibitors (ICI), which can enhance antitumor immune responses, have revolutionized the...
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