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TACE Combined with Ralox-HAIC (Oxaliplatin Puls Raltitrexed) and System Therapy in Patients with Unresectable Hepatocellular Carcinoma
TACE Combined with Ralox-HAIC (Oxaliplatin Puls Raltitrexed) and System Therapy in Patients with Unresectable Hepatocellular Carcinoma
To analyze the efficacy and safety of TACE combined with Ralox-HAIC and systemic therapy in patients with uHCC treated bet...
Hepatocellular Carcinoma Precursor Lesions: From Pathological Basis to Risk Stratification and Precision Intervention
Hepatocellular Carcinoma Precursor Lesions: From Pathological Basis to Risk Stratification and Precision Intervention
Reviewing the pathological basis, malignant potential, diagnostic approaches, risk stratification strategies, and precisio...
Putative Imprinting Control Regions with Aberrant Blood-Based DNA Methylation are Associated with Hepatocellular Carcinoma Risk
Putative Imprinting Control Regions with Aberrant Blood-Based DNA Methylation are Associated with Hepatocellular Carcinoma Risk
Identifying putative ICRs with aberrant DNA methylation associated with HCC to develop a blood-based risk stratification p...
A Machine Learning Guided System for Therapeutic Decision-Making in Intra-Arterial Therapy of Hepatocellular Carcinoma
A Machine Learning Guided System for Therapeutic Decision-Making in Intra-Arterial Therapy of Hepatocellular Carcinoma
The present study aimed to develop and validate an ML model based on clinical data from uHCC patients who received IAT
Machine Learning-Based Radiopatho-Clinical Model Integrating Ultrasound Radiomics and Kleiner Score for Prognosis Prediction in NAFLD-Related Hepatocellular Carcinoma
Machine Learning-Based Radiopatho-Clinical Model Integrating Ultrasound Radiomics and Kleiner Score for Prognosis Prediction in NAFLD-Related Hepatocellular Carcinoma
Machine learning model integrating ultrasound radiomics, steatosis grading, and clinical data predicted HCC outcomes post-...
Current Status and Emerging Trends in Global Research on Liposome Therapy for Hepatocellular Carcinoma: A Bibliometric Analysis
Current Status and Emerging Trends in Global Research on Liposome Therapy for Hepatocellular Carcinoma: A Bibliometric Analysis
this study seeks to identify emerging research directions and translational challenges that may inform future therapeutic ...
Integrating Combination Therapy and Smart Embolic Materials to Overcome the Therapeutic Ceiling of Transarterial Chemoembolization in Hepatocellular Carcinoma
Integrating Combination Therapy and Smart Embolic Materials to Overcome the Therapeutic Ceiling of Transarterial Chemoembolization in Hepatocellular Carcinoma
Evaluating clinical evidence for TACE-based combinations and principles guiding individualized selection in HCC to improve...
Multimodal Modeling Distinguishes Treatment Response from Overall Survival in Hepatocellular Carcinoma Receiving Combined Interventional and Targeted Immunotherapy
Multimodal Modeling Distinguishes Treatment Response from Overall Survival in Hepatocellular Carcinoma Receiving Combined Interventional and Targeted Immunotherapy
Short-term response and long-term survival in HCC are distinct clinical endpoints associated with different biological dri...
Angiogenic Prognostic Signature for Stratification in Hepatocellular Carcinoma
Angiogenic Prognostic Signature for Stratification in Hepatocellular Carcinoma
We established a robust ARG‑based prognostic signature for HCC that improves risk stratification
Machine-Learning Based Prognostic Model for Predicting Early Recurrence in HCC Patients After Hepatectomies: An Explainable AI Approach
Machine-Learning Based Prognostic Model for Predicting Early Recurrence in HCC Patients After Hepatectomies: An Explainable AI Approach
Evaluating explainable machine learning (ML) architectures to optimize risk modeling using readily accessible parameters
Emerging Role of Sirtuins-Mediated Ferroptosis in Hepatocellular Carcinoma Progression: Mechanisms and Therapeutic Perspectives
Emerging Role of Sirtuins-Mediated Ferroptosis in Hepatocellular Carcinoma Progression: Mechanisms and Therapeutic Perspectives
Roles and mechanisms of sirtuins in mediating ferroptosis in hepatocellular carcinoma
Baseline Sleep Quality and Objective Response in HCC Patients Treated with TACE Combined with Lenvatinib and PD-1 Inhibitors: A Secondary Analysis of a Prospectively Registered Observational Cohort
Baseline Sleep Quality and Objective Response in HCC Patients Treated with TACE Combined with Lenvatinib and PD-1 Inhibitors: A Secondary Analysis of a Prospectively Registered Observational Cohort
Poor baseline sleep quality predicted lower treatment response in HCC patients receiving TACE, lenvatinib, and PD-1 inhibi...
Preoperative Prediction of Glypican-3 Expression in Hepatocellular Carcinoma Using Sonazoid Contrast-Enhanced Ultrasound Radiomics
Preoperative Prediction of Glypican-3 Expression in Hepatocellular Carcinoma Using Sonazoid Contrast-Enhanced Ultrasound Radiomics
This study aims to develop a radiomics approach using Sonazoid CEUS to predict GPC3 status and its association with early RFS
Etiology-Driven Mouse Models of Hepatocellular Carcinoma: Paving the Way for Precision Oncology
Etiology-Driven Mouse Models of Hepatocellular Carcinoma: Paving the Way for Precision Oncology
Etiology-aligned GEMMs can help match biological questions to appropriate preclinical platforms and generate testable hypo...
SPP1+ Macrophages Promote Immunosuppression in Post-TACE Hepatocellular Carcinoma Involving Lactate-Induced Lactylation and Potential SPP1-CD44 Signaling
SPP1+ Macrophages Promote Immunosuppression in Post-TACE Hepatocellular Carcinoma Involving Lactate-Induced Lactylation and Potential SPP1-CD44 Signaling
Targeting lactate-induced lactylation or the potential SPP1-CD44 interaction may offer promising therapeutic opportunities
Correlation of Insulin and/or Insulin Secretagogues with the Risk of Hepatocellular Carcinoma and All-Cause Mortality Among Patients with Chronic Hepatitis B and Type 2 Diabetes Mellitus: A Retrospective Cohort Study
Correlation of Insulin and/or Insulin Secretagogues with the Risk of Hepatocellular Carcinoma and All-Cause Mortality Among Patients with Chronic Hepatitis B and Type 2 Diabetes Mellitus: A Retrospective Cohort Study
Exploring the association of insulin and/or insulin secretagogues with the risk of HCC and all-cause mortality among patie...
Efficacy and Safety of Modified Sishen Decoction for Tyrosine Kinase Inhibitor-Induced Diarrhea in Hepatocellular Carcinoma: A Randomized Controlled Trial
Efficacy and Safety of Modified Sishen Decoction for Tyrosine Kinase Inhibitor-Induced Diarrhea in Hepatocellular Carcinoma: A Randomized Controlled Trial
this RCT was conducted to evaluate the clinical efficacy and safety of modified Sishen decoction in the treatment of TKI-i...
Tumor Burden Thresholds Associated with Successful Downstaging After Yttrium-90 Radioembolization in Hepatocellular Carcinoma Beyond UCSF Criteria
Tumor Burden Thresholds Associated with Successful Downstaging After Yttrium-90 Radioembolization in Hepatocellular Carcinoma Beyond UCSF Criteria
Exploring factors associated with successful HCC downstaging and potential selection thresholds remain unclear.
SNHG6 Promotes Lipid Metabolic Reprogramming in Hepatocellular Carcinoma via Upregulation of SCD
SNHG6 Promotes Lipid Metabolic Reprogramming in Hepatocellular Carcinoma via Upregulation of SCD
Role and molecular mechanism of the long non-coding RNA small nucleolar RNA host gene 6 in lipid metabolic reprogramming i...
Prognostic Relevance of Neddylation-Related Genes in Hepatocellular Carcinoma
Prognostic Relevance of Neddylation-Related Genes in Hepatocellular Carcinoma
Identifying genes linked to hepatocellular carcinoma prognosis associated with neddylation through bioinformatics.
Early PIVKA-II Response Predicts Treatment Efficacy of Immune Checkpoint Inhibitors in Patients with Advanced Hepatocellular Carcinoma
Early PIVKA-II Response Predicts Treatment Efficacy of Immune Checkpoint Inhibitors in Patients with Advanced Hepatocellular Carcinoma
Evaluating the predictive value of another hepatocellular carcinoma tumor marker, protein induced by vitamin K absence/ant...
Immunotherapy-Based Strategies versus Transcatheter Arterial Chemoembolization and the Impact of Treatment Duration in Hepatocellular Carcinoma with Microvascular Invasion: A Retrospective Multicenter Cohort Study
Immunotherapy-Based Strategies versus Transcatheter Arterial Chemoembolization and the Impact of Treatment Duration in Hepatocellular Carcinoma with Microvascular Invasion: A Retrospective Multicenter Cohort Study
This study compares ICI-based therapy with TACE in a real-world postoperative setting and to assess whether extended ICI t...
P-ART Score is a New Modification to Improve ART Score Predictive Accuracy for Patients with HCC Undergoing TACE
P-ART Score is a New Modification to Improve ART Score Predictive Accuracy for Patients with HCC Undergoing TACE
Evaluate the Assessment for Retreatment with TACE score in predicting survival after trans-arterial chemoembolization in h...
The Long Non-Coding RNA SNHG16 Negatively Regulates Let-7 and Predicts Recurrence in Hepatocellular Carcinoma
The Long Non-Coding RNA SNHG16 Negatively Regulates Let-7 and Predicts Recurrence in Hepatocellular Carcinoma
This study screened 12 members of the let-7 family & their related lncRNAs. We then selected targets that have predict...
Postoperative Adjuvant Transcatheterarterial Chemoembolization Should Be Considered Selectively for Patients with Cytokeratin-19 Positive Hepatocellular Carcinoma
Postoperative Adjuvant Transcatheterarterial Chemoembolization Should Be Considered Selectively for Patients with Cytokeratin-19 Positive Hepatocellular Carcinoma
Evaluating clinical efficacy of postoperative adjuvant transarterial chemoembolization in cytokeratin 19-positive hepatoce...
Spontaneous Rupture of Hepatocellular Carcinoma: Pathogenesis, Clinical Management, Prognostic Factors, and Future Directions
Spontaneous Rupture of Hepatocellular Carcinoma: Pathogenesis, Clinical Management, Prognostic Factors, and Future Directions
By integrating available data and highlighting unresolved questions, we hope to guide clinical practice and inform the des...
Cms1 Ribosomal Small Subunit Homolog Promotes HCC Proliferation and Migration by Modulating the TNF/NF-κB Signaling Pathway
Cms1 Ribosomal Small Subunit Homolog Promotes HCC Proliferation and Migration by Modulating the TNF/NF-κB Signaling Pathway
In the study, we provided novel insights into the mechanism of CMSS1 in HCC progression.
The Role of Nuclear Medicine in Predicting Treatment Response to Immunotherapy and Targeted Therapy in Hepatocellular Carcinoma: A Narrative Review
The Role of Nuclear Medicine in Predicting Treatment Response to Immunotherapy and Targeted Therapy in Hepatocellular Carcinoma: A Narrative Review
Nuclear medicine holds potential for identifying patients who are likely to benefit from targeted and immunotherapy.
Predictive Value of Hepatic Steatosis for Postoperative Recurrence in Hepatitis B-Related Hepatocellular Carcinoma: Development of a Machine Learning-Based Prognostic Model
Predictive Value of Hepatic Steatosis for Postoperative Recurrence in Hepatitis B-Related Hepatocellular Carcinoma: Development of a Machine Learning-Based Prognostic Model
This study shows that preoperative hepatic steatosis is an independent risk factor for postoperative recurrence in HBV-rel...
ANT Score Nomogram for Predicting Very Early Recurrence of Hepatocellular Carcinoma
ANT Score Nomogram for Predicting Very Early Recurrence of Hepatocellular Carcinoma
we developed and validated the ANT Score, a novel prognostic model that integrates nutrition, inflammation, and tumor burd...
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