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Glioblastoma survival in rural America: a 10-year experience from a quaternary care center
Glioblastoma survival in rural America: a 10-year experience from a quaternary care center
Glioblastoma (GBM) is the most aggressive primary brain tumor with dismal prognosis. Patients residing in rural and Appala...
Malignant transformation in IDH-mutant gliomas: clinical drivers and survival outcomes in a histologically defined cohort
Malignant transformation in IDH-mutant gliomas: clinical drivers and survival outcomes in a histologically defined cohort
The predictors and prognostic implications of malignant transformation (MT) in IDH-mutant gliomas remain incompletely defi...
Reduced dose single-fraction frame-based postoperative radiosurgery for large (> 10 cm) brain metastases cavities: real world outcomes
Reduced dose single-fraction frame-based postoperative radiosurgery for large (> 10 cm) brain metastases cavities: real world outcomes
At our institution, large resection cavities (LRC) of brain metastases (BRM) are typically treated with reduced dose (RD),...
Emerging systemic treatment strategies for vestibular schwannoma
Emerging systemic treatment strategies for vestibular schwannoma
While vestibular schwannomas (VS) have traditionally been managed with surgery and radiation, systemic targeted therapies ...
Individualized prediction of survival after brain metastasis development in patients with breast cancer
Individualized prediction of survival after brain metastasis development in patients with breast cancer
Individuals with breast cancer are at high risk for developing brain and central nervous system metastases (BrM), which ar...
Correction to: Phosphoenolpyruvate carboxykinase 2 as a prognostic biomarker: expression and clinical significance in Group 3 and Group 4 medulloblastoma
Correction to: Phosphoenolpyruvate carboxykinase 2 as a prognostic biomarker: expression and clinical significance in Group 3 and Group 4 medulloblastoma
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4....
Socioeconomic disparities in -wildtype glioblastoma survival: interactions between age and household income in a SEER cohort
Socioeconomic disparities in -wildtype glioblastoma survival: interactions between age and household income in a SEER cohort
Glioblastoma multiforme (GBM) remains an aggressive brain tumor with a poor prognosis. The financial burden of GBM have ra...
Prognostic relevance of resection at first recurrence in isocitrate dehydrogenase mutant lower-grade glioma: results from a retrospective, single-center, volumetric analysis
Prognostic relevance of resection at first recurrence in isocitrate dehydrogenase mutant lower-grade glioma: results from a retrospective, single-center, volumetric analysis
The prognostic role of repeat resection in IDH-mutant lower-grade glioma remains insufficiently defined. This observationa...
Immunotherapy approaches for the treatment of relapsed or progressive medulloblastoma
Immunotherapy approaches for the treatment of relapsed or progressive medulloblastoma
Immunotherapy provides a novel and alternative treatment strategy to improve the outcomes in patients with refractory medu...
MGMT downregulation by CRISPR/Cas13 RNA-guided RNA targeting enhances glioma cell sensitivity to TMZ chemotherapy
MGMT downregulation by CRISPR/Cas13 RNA-guided RNA targeting enhances glioma cell sensitivity to TMZ chemotherapy
Current standard of care for glioblastoma involves fractionated radiotherapy administered with Temozolomide (TMZ), a DNA-a...
Associations of surgical menopause and hormone replacement therapy with meningioma development
Associations of surgical menopause and hormone replacement therapy with meningioma development
Bilateral salpingo-oophorectomy (BSO) and hormone replacement therapy (HRT) exert opposing effects on systemic sex hormone...
Longitudinal changes of neurocognitive function and ALPS-index in patients with brain tumors receiving brain irradiation
Longitudinal changes of neurocognitive function and ALPS-index in patients with brain tumors receiving brain irradiation
Neurocognitive decline is common after brain radiotherapy (RT), but underlying mechanisms remain unclear. Altered glymphat...
Endogenous immune recruitment in glioblastoma CAR T therapy: cytokine, myeloid, and chemokine circuitry
Endogenous immune recruitment in glioblastoma CAR T therapy: cytokine, myeloid, and chemokine circuitry
Glioblastoma (GBM) has remained relatively unresponsive to immunotherapy, with scattered durable responses reported in ear...
Neurocognitive functioning, seizure control, and return to work after awake surgery with or without adjuvant therapy in -mutant grade 3 diffuse gliomas
Neurocognitive functioning, seizure control, and return to work after awake surgery with or without adjuvant therapy in -mutant grade 3 diffuse gliomas
The optimal oncological management of adult patients with IDH-mutant CNS WHO grade 3 diffuse gliomas remains debated, part...
pneumonia in patients with CNS tumors receiving dexamethasone: clinical outcomes and prophylaxis gaps
pneumonia in patients with CNS tumors receiving dexamethasone: clinical outcomes and prophylaxis gaps
Pneumocystis jirovecii pneumonia (PCP) now predominantly affects non-HIV immunocompromised patients, with corticosteroid e...
Application of enhanced recovery after surgery for patients with spinal metastasis: a systematic review and meta-analysis
Application of enhanced recovery after surgery for patients with spinal metastasis: a systematic review and meta-analysis
Enhanced Recovery After Surgery (ERAS) has been used to improve recovery and outcomes after surgical operations. However, ...
Spinal cord compression at initial presentation in pediatric oncology patients: neurological sequelae and survival outcomes
Spinal cord compression at initial presentation in pediatric oncology patients: neurological sequelae and survival outcomes
Symptom duration > 28 days predicted neurological sequelae with high accuracy (AUC = 0.865)...
Patterns of failure following stereotactic radiosurgery salvage for recurrent high-grade glioma
Patterns of failure following stereotactic radiosurgery salvage for recurrent high-grade glioma
Re-irradiation with stereotactic radiosurgery (SRS) is an increasingly used treatment for recurrent high-grade glioma (HGG...
Tunneling nanotubes between glioblastoma cells and T cells and hijack of mitochondria
Tunneling nanotubes between glioblastoma cells and T cells and hijack of mitochondria
Glioblastoma is a highly aggressive and invasive brain tumor that can interact dynamically with its surrounding tumor micr...
Prevalence, therapeutic approaches, and survival rates of brain metastases in non-small cell lung cancer: a multi-institutional claims-based study from 2014 to 2024
Prevalence, therapeutic approaches, and survival rates of brain metastases in non-small cell lung cancer: a multi-institutional claims-based study from 2014 to 2024
Brain metastases (BM) cause substantial morbidity and mortality in patients with non-small cell lung cancer (NSCLC). Updat...
Incidence, demographics, and survival of patients with brain metastases from stage IV colorectal cancer: a population-based study from 2013 to 2023
Incidence, demographics, and survival of patients with brain metastases from stage IV colorectal cancer: a population-based study from 2013 to 2023
Colorectal cancer (CRC) is the third most common cancer globally with rising incidence in the young population. While rare...
Dietary habits in relation to outcome and therapy-related toxicity in patients with glioblastoma – a retrospective cohort study
Dietary habits in relation to outcome and therapy-related toxicity in patients with glioblastoma – a retrospective cohort study
Glioblastoma is the most prevalent primary malignant brain tumour in adults and bears poor survival. Data on associations ...
facilitates glioma progression and is associated with the KRAS/ERK pathway
facilitates glioma progression and is associated with the KRAS/ERK pathway
Glioma is the most common primary brain and spinal cord tumor, with effective treatments still lacking. Stress-activated p...
Stereotactic radiosurgery for recurrent high-grade gliomas: a systematic review
Stereotactic radiosurgery for recurrent high-grade gliomas: a systematic review
Management of recurrent high-grade glioma (rHGG) is challenging. Contemporary therapeutic approaches include systemic chem...
Hemagglutinating virus of Japan envelope encapsulating microRNA-34a-5p robustly induces apoptosis of malignant meningioma cells by suppressing survivin
Hemagglutinating virus of Japan envelope encapsulating microRNA-34a-5p robustly induces apoptosis of malignant meningioma cells by suppressing survivin
Malignant meningiomas are characterized by high recurrence rates and limited therapeutic options beyond surgery and radiat...
F-NOTA-NFB PET/MRI in glioma recurrence: comparison with C-methionine PET/MRI and contrast-enhanced MRI
F-NOTA-NFB PET/MRI in glioma recurrence: comparison with C-methionine PET/MRI and contrast-enhanced MRI
To investigate the clinical utility of 18F-NOTA-NFB PET/MRI relative to 11C-methionine (11C-MET) PET/MRI and contrast-enha...
Emerging trends in cell-based therapies: contemporary advances and ethical considerations in translational neurosurgical oncology
Emerging trends in cell-based therapies: contemporary advances and ethical considerations in translational neurosurgical oncology
Emerging cell-based therapies represent a promising advancement in neurosurgical oncology, offering novel therapeutic poss...
Enhancing the therapeutic effect on tumor cells through wireless optoelectronic stimulation
Enhancing the therapeutic effect on tumor cells through wireless optoelectronic stimulation
Drug resistance is a major challenge in the treatment of tumor diseases, especially in glioblastoma (GBM), where temozolom...
Clinical and neuropathological criteria for distinguishing between IDH-mutant astrocytomas of WHO grade 2 and 3
Clinical and neuropathological criteria for distinguishing between IDH-mutant astrocytomas of WHO grade 2 and 3
The 2021 WHO classification of CNS tumors allows flexibility in the grading of IDH-mutant astrocytic gliomas, leading to s...
Stereotactic radiosurgery for intracranial and spinal adenoid cystic carcinoma: systematic review and illustrative case presentation
Stereotactic radiosurgery for intracranial and spinal adenoid cystic carcinoma: systematic review and illustrative case presentation
Adenoid cystic carcinoma (ACC) is a rare, aggressive malignancy with a predilection for perineural spread and distant meta...
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