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Cellular uptake of 2‐aminopyridine‐modified peptide nucleic acids conjugated with cell‐penetrating peptides
Cellular uptake of 2‐aminopyridine‐modified peptide nucleic acids conjugated with cell‐penetrating peptides
Abstract Cell-penetrating peptides (CPPs) have been extensively used to deliver peptide nucleic acid (PNA) in cells. We ha...
DNA‐assisted site‐selective protein modification
DNA‐assisted site‐selective protein modification
Abstract Protein modification is important for various types of biomedical research, including proteomics and therapeutics...
Cover Image
Cover Image
Endotoxin exists on the outer membrane of Gram-negative bacteria and poses risks to human health by triggering a series of...
Cyclopentane peptide nucleic acid: Gold nanoparticle conjugates for the detection of nucleic acids in a microfluidic format
Cyclopentane peptide nucleic acid: Gold nanoparticle conjugates for the detection of nucleic acids in a microfluidic format
Abstract Routine patient testing for viral infections is critical to identify infected individuals for treatment and to pr...
A comparison between β‐tricalcium phosphate verse chitosan poly‐caprolactone‐based 3D melt extruded composite scaffolds
A comparison between β‐tricalcium phosphate verse chitosan poly‐caprolactone‐based 3D melt extruded composite scaffolds
Abstract Melt extrusion 3D printing has become an attractive additive manufacturing technology to construct degradable sca...
Identifying N7‐methylguanosine sites by integrating multiple features
Identifying N7‐methylguanosine sites by integrating multiple features
Abstract Recent studies reported that N7-methylguanosine (m7G) plays a vital role in gene expression regulation. As a cons...
Fold‐switching proteins
Fold‐switching proteins
1 WHERE THE FIELD OF FOLD-SWITCHING PROTEINS STANDS TODAY This special issue of Biopolymers is dedicate...
Folding dynamics of polymorphic G‐quadruplex structures
Folding dynamics of polymorphic G‐quadruplex structures
Abstract G-quadruplexes (G4), found in numerous places within the human genome, are involved in essential processes of cel...
Rapid, multiplexed detection of the let‐7 miRNA family using γPNA amphiphiles in micelle‐tagging electrophoresis
Rapid, multiplexed detection of the let‐7 miRNA family using γPNA amphiphiles in micelle‐tagging electrophoresis
Abstract miRNA is a promising class of biomarkers whose levels can be assayed to detect various forms of cancer and other ...
Mechanisms and applications of peptide nucleic acids selectively binding to double‐stranded RNA
Mechanisms and applications of peptide nucleic acids selectively binding to double‐stranded RNA
Abstract RNAs form secondary structures containing double-stranded base paired regions and single-stranded regions. Probin...
Identification and characterization of metamorphic proteins: Current and future perspectives
Identification and characterization of metamorphic proteins: Current and future perspectives
Abstract Proteins that can reversibly alternate between distinctly different folds under native conditions are described a...
A simple fluorescent assay for the detection of peptide nucleic acid‐directed double strand duplex invasion
A simple fluorescent assay for the detection of peptide nucleic acid‐directed double strand duplex invasion
Abstract Peptide nucleic acid (PNA) is a mimic of nucleic acids that is able to bind complementary oligonucleotides with h...
A sequence‐based method for predicting extant fold switchers that undergo α‐helix ↔ β‐strand transitions
A sequence‐based method for predicting extant fold switchers that undergo α‐helix ↔ β‐strand transitions
Abstract Extant fold-switching proteins remodel their secondary structures and change their functions in response to cellu...
Spectroscopic, thermodynamic and kinetic analysis of selective triplex formation by peptide nucleic acid with double‐stranded RNA over its DNA counterpart
Spectroscopic, thermodynamic and kinetic analysis of selective triplex formation by peptide nucleic acid with double‐stranded RNA over its DNA counterpart
Abstract Unlike conventional triplex-forming oligonucleotide (TFO), triplex-forming peptide nucleic acid (PNA) can tightly...
Polydopamine nanofilms for high‐performance paper‐based electrochemical devices
Polydopamine nanofilms for high‐performance paper‐based electrochemical devices
Abstract Since the discovery of polydopamine (PDA), there has been a lot of progress on using this substance to functional...
Hierarchical assemblies of polypeptoids for rational design of advanced functional nanomaterials
Hierarchical assemblies of polypeptoids for rational design of advanced functional nanomaterials
Abstract Polypeptoids (poly-N-substituent glycines) are a class of highly tailorable peptidomimetic polymers. Polypeptoids...
Low endotoxin recovery and its impact on endotoxin detection
Low endotoxin recovery and its impact on endotoxin detection
Abstract Endotoxin exists on the outer membrane of Gram-negative bacteria and poses risks to human health by triggering a ...
Effect of amino acid composition of elastin‐like polypeptide nanoparticles on nonspecific protein adsorption, macrophage cell viability and phagocytosis
Effect of amino acid composition of elastin‐like polypeptide nanoparticles on nonspecific protein adsorption, macrophage cell viability and phagocytosis
Abstract Development of elastin-like polypeptide (ELP) biomaterials is widespread, but information critical for clinical d...
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