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Cytokine-mediated intrinsic and extrinsic regulation of anti-tumor adoptive T cell therapy
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The role of osteoprotegerin in colorectal cancer: Molecular interactions, mechanistic insights, and therapeutic implications
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Role of FOXO3 in regulation of redox homeostasis and promotion of red blood cell longevity in sickle cell disease
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Fibroblast growth factor homologous factors in neural signaling: Molecular mechanisms and disease-relevant dysregulation
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Designing next-generation interleukin immunotherapy: A cytokine-guided framework for precision cancer therapy
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Temporal dynamics of type I interferon signaling in checkpoint inhibitor response and resistance
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Inflammatory Mechanisms in the AML Bone Marrow Niche: From Pathogenesis to Therapy
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Tissue-resident immune cells in tumors: Cytokine-mediated regulation, functional plasticity, and therapeutic opportunities
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The functional roles of macrophage migration inhibitory factor in the tumor microenvironment
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Retinoid dynamics in immune cells during age-related diseases
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The role of cellular senescence in metabolic dysfunction-associated steatotic liver disease
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The role of tyrosine phosphorylation in modulating death receptor signaling
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The multifaceted roles of IL-1β in Alzheimer’s disease: From pathogenic amplifier to neuroimmune modulator
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NK cell adaptation in the tumor microenvironment: Insights for NK cell-based immunotherapy
The discovery of NK cells in 1975 unveiled a lymphocyte population capable of lysing malignant cells without prior sensiti...
Arteriolar angiogenesis: implications in anti-angiogenic immunotherapy for pancreatic cancers
Angiogenesis, described as a biological process from which new blood vessels develop from pre-existent ones, is closely as...
Pancreatic cancer exosomes: Their role in drug resistance and immunomodulation
Pancreatic ductal adenocarcinoma (PDAC) is a truly lethal malignancy worldwide. This indisposed prognosis of PDAC is a dir...
Role of cytokine-based immunotherapy approaches in gastrointestinal cancers
Gastrointestinal (GI) cancers, encompassing malignancies of the esophagus, stomach, pancreas, liver, colorectum, and other...
Targeting cytokines: Reshaping the pancreatic tumor microenvironment
Inflammation is a key part of tumor development, progression, and metastasis. Inflammation is a part of the host defensive...
Nanotechnology-based cytokine delivery strategies in gastrointestinal cancers
Although considerable progress has been made in diagnostic and therapeutic strategies, cancer continues to represent a maj...
SARS-CoV-2 innate immune recognition and implications for respiratory health
Dr. Yohannes Afework Mebratu: Biography Dr. Yohannes Afework Mebratu is a molecular biologist and an Assistant Professor i...
Tightly bound T-cell clusters: A new class of hyper-effector tumor killers
Wenxue Ma, MD, PhD, is a specialist in Immuno-Oncology, physician scientist, and director of drug discovery at Sanford Ste...
The Cytokine–Skin Barrier Axis in Health and Disease
Maria Victoria Souto-Silva is a doctoral candidate at the Interdisciplinary Biosciences Laboratory, University of Brasília...
Post COVID-19 pandemic Inflammatory Insights into Cancer: Consequences for immunotherapy
Prof Anna-Mart Engelbrecht Anna-Mart Engelbrecht is a Professor of Physiological Sciences at Stellenbosch University, wher...
The IL-17 axis in gastric carcinogenesis: From inflammation to oncogenic transformation
Prof. Dr. Lei Huang (ORCiD: https://orcid.org/0000–0002–4225–9200), Principal Investigator leading the "Digestive Inflamma...
Meteorin-like/Metrnl: A pleiotropic cytokine implicated in metabolic, inflammatory and malignant disorders
Professor Guangda Xiang(corresponding author), M.D. & Ph.D. He is a chief physician at department of endocrinology, ge...
Emerging involvement of CXCL13 in cancer development and progression
George S. Karagiannis, D.V.M, Ph.D., is an assistant professor in the Department of Microbiology and Immunology at the Alb...