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Profiling Unique Proteins in Stable COPD: Uncovering Novel Biomarker Candidates and Pathophysiological Mechanisms
Profiling Unique Proteins in Stable COPD: Uncovering Novel Biomarker Candidates and Pathophysiological Mechanisms
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder. Despite the high morbidity and mortali...
The Determination of Inorganic Cations and Low-Molecular-Mass Anions in Serum by Capillary Zone Electrophoresis
The Determination of Inorganic Cations and Low-Molecular-Mass Anions in Serum by Capillary Zone Electrophoresis
Capillary zone electrophoresis (CZE) was employed to quantify major cations (K+, Na+, Ca2+, Mg2+) and anions (Cl−, $...
Diethanolammonium Salts of Fatty Acids Enhance the Solubilization and Antitumor Activity of Palmitoyl and Stearoyl Diethanolamides In Vitro
Diethanolammonium Salts of Fatty Acids Enhance the Solubilization and Antitumor Activity of Palmitoyl and Stearoyl Diethanolamides In Vitro
Fatty acid ethanolamides exhibit a variety of biological effects. Recently, it has been shown that diethanolamides of palm...
Analysis of the Structure of Salivary Lipids by FTIR Spectroscopy in Mammary Gland Pathologies
Analysis of the Structure of Salivary Lipids by FTIR Spectroscopy in Mammary Gland Pathologies
An analysis of saliva lipid extracts using Fourier transform infrared spectroscopy was performed in breast cancer, fibroad...
Dacarbazine Increases Melanoma BRO Cell Adhesion to the Extracellular Matrix Components
Dacarbazine Increases Melanoma BRO Cell Adhesion to the Extracellular Matrix Components
Melanoma is one of the most dangerous malignant tumors. The number of melanoma cases is increasing especially in light ski...
Substance Addiction Development:
Substance Addiction Development:
Gut microbiota can influence the central nervous system through the transport of microbial metabolites by the microbiota&#...
Full Transcriptome Analysis of the Liver of Rats Receiving the Complex of L-Carnitine and Resveratrol in the Composition of a Standard or Hypercaloric Diet
Full Transcriptome Analysis of the Liver of Rats Receiving the Complex of L-Carnitine and Resveratrol in the Composition of a Standard or Hypercaloric Diet
The use of resveratrol and L-carnitine (RC) in the complex as components of dietary products and food supplements is consi...
Serine Hydroxymethyltransferase in Cancer Cells
Serine Hydroxymethyltransferase in Cancer Cells
The nonessential amino acids serine and glycine play an important role in the human organism. They are necessary for the s...
Relationship between Hydration and Catalytic Activity of Endonucleases: The Case of Cas9 and Its Evolutionary Variants
Relationship between Hydration and Catalytic Activity of Endonucleases: The Case of Cas9 and Its Evolutionary Variants
This study examined the structures of SpCas9 endonuclease of Streptococcus pyogenes and their evolutionary variants using ...
Phyto-Therapeutic Potential of Medicinal Plant Extracts against MDR Pathogens and Their Cytotoxicity
Phyto-Therapeutic Potential of Medicinal Plant Extracts against MDR Pathogens and Their Cytotoxicity
Plant extracts can be great substitutes to the infections instigated by multidrug-resistant (MDR) microbes due to the pres...
The Role of hnRNPA2/B1 in Hepatitis B Virus Replication and Transcription
The Role of hnRNPA2/B1 in Hepatitis B Virus Replication and Transcription
hnRNPA2/B1 is an RNA-binding protein involved in the regulation of transcription, mRNA stability, and also functions as on...
Cytotoxic and Cytostatic Properties of Lichen Depsidones (Review)
Cytotoxic and Cytostatic Properties of Lichen Depsidones (Review)
Lichens are producers of a number of unique secondary metabolites. The most numerous and structurally diverse group of com...
Determination of Potassium and Sodium in Blood Serum in Patients with Lymphoproliferative Diseases
Determination of Potassium and Sodium in Blood Serum in Patients with Lymphoproliferative Diseases
The levels of potassium and sodium ions and their ratio (Na+/K+) were assessed in the blood serum of 54 healthy donors, as...
Investigation of Antibacterial Activity of Zinc Oxide and ZnO@Ag Nanoparticles Prepared by Plant
Investigation of Antibacterial Activity of Zinc Oxide and ZnO@Ag Nanoparticles Prepared by Plant
We report a green synthesis of ZnO and ZnO@Ag nanostructures using an aqueous extract of Spinacia oleracea as a reducing a...
Innovative Approaches in Nanomedicine: Atomic Layer Deposition of Antibacterial Nanofilms and Their Application in the Treatment of Chronic Wounds
Innovative Approaches in Nanomedicine: Atomic Layer Deposition of Antibacterial Nanofilms and Their Application in the Treatment of Chronic Wounds
The paper presents a review of the application of nanotechnology in medicine (nanomedicine) in Russia and abroad. Particul...
Molecular Triad of MTR, Homocysteine, and 5-MTHF in HCC: Towards Novel Diagnostic Markers
Molecular Triad of MTR, Homocysteine, and 5-MTHF in HCC: Towards Novel Diagnostic Markers
Hepatocellular carcinoma (HCC) is a major cause of cancer-related deaths globally. In HCC, metabolic reprogramming leads t...
Activating Effect of Avarol and Damiron A from Sea Sponges on α-N-Acetylgalactosaminidase from Human Colorectal Cancer Cell Cultures
Activating Effect of Avarol and Damiron A from Sea Sponges on α-N-Acetylgalactosaminidase from Human Colorectal Cancer Cell Cultures
α-N-Acetylgalactosaminidase (α-NaGalase) is produced by all cancer tumors and accumulates in the plasma of patie...
Elucidation of the Interaction of Human Serum Albumin with Linoleic Acid Using Spectroscopic, Docking, and Molecular Dynamic Simulation Techniques
Elucidation of the Interaction of Human Serum Albumin with Linoleic Acid Using Spectroscopic, Docking, and Molecular Dynamic Simulation Techniques
Linoleic acid (LA) is a fatty acid that cannot be synthesized by the body and is primarily found in plant seeds. It acts a...
Isolation, Identification, and Cytotoxicity of α-Alectoronic and α-Collatolic Acids Isolated from the Lichen
Isolation, Identification, and Cytotoxicity of α-Alectoronic and α-Collatolic Acids Isolated from the Lichen
The results of the study on isolation, purification, and study of the cytotoxicity of α-alectoronic and α-collat...
Hepatitis C Specificity in Lowering Serum Lipids of Patients with Chronic Renal Failure
Hepatitis C Specificity in Lowering Serum Lipids of Patients with Chronic Renal Failure
This study describes the effects of the hepatitis C virus on lipid profile and some other parameters in patients with CRF....
Evaluation of Ornithine Decarboxylase and Ferric Reducing Capacity Levels as Potential Biomarkers for Polycystic Ovary Syndrome
Evaluation of Ornithine Decarboxylase and Ferric Reducing Capacity Levels as Potential Biomarkers for Polycystic Ovary Syndrome
Background: Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder affecting reproductive-age women, often link...
Regenerative Medicine Technologies in Dentistry: Tissue Engineering in Dental Implantation
Regenerative Medicine Technologies in Dentistry: Tissue Engineering in Dental Implantation
In recent years, regenerative medicine technologies, especially tissue engineering, have been increasingly used in dental ...
Rhizome Lectin Induces Apoptosis in Human Lung Cancer Cells and Inhibits the Growth of Ehrlich Ascites Carcinoma Cells in Mice
Rhizome Lectin Induces Apoptosis in Human Lung Cancer Cells and Inhibits the Growth of Ehrlich Ascites Carcinoma Cells in Mice
Geodoram densiflorum or pink nodding orchid grows in wet habitats in Bangladesh. Rural people traditionally use this orchi...
Relationship between the Level of Alcohol Use and the Concentrations of Some Neuropeptides and Proteins in Blood Serum
Relationship between the Level of Alcohol Use and the Concentrations of Some Neuropeptides and Proteins in Blood Serum
The development of novel highly informative approaches to the assessment of chronic alcohol use is still an urgent problem...
Indole-3-carbinol and Different Classes of Polyphenols in the Regulation of the Activity of the Nrf2/Keap1/ARE Signaling System
Indole-3-carbinol and Different Classes of Polyphenols in the Regulation of the Activity of the Nrf2/Keap1/ARE Signaling System
Nutriome is a set of alimentary factors for maintaining the body’s adaptive potential. Of particular importance for ...
Thrombopoiesis and Androgen Biosynthesis in Patients with Adrenal Cortex Tumors
Thrombopoiesis and Androgen Biosynthesis in Patients with Adrenal Cortex Tumors
The results of experimental and clinical studies indicate the involvement of platelets in the process of progression of ma...
Potential Influence of Tryptophan Metabolites on Translocation of Bacterial DNA into the Blood in Normal Conditions and in Various Obesity Phenotypes
Potential Influence of Tryptophan Metabolites on Translocation of Bacterial DNA into the Blood in Normal Conditions and in Various Obesity Phenotypes
It is known that obesity changes the permeability of the intestinal wall, including for bacterial DNA. Therefore, obese pa...
Bile Acid Profiling for Differential Diagnosis of Hepatobiliary Cancers and Cholelitiasis
Bile Acid Profiling for Differential Diagnosis of Hepatobiliary Cancers and Cholelitiasis
Cholangiocarcinoma (CCA) and pancreatic ductal adenocarcinoma (PDAC) are malignant tumors that can be characterized by low...
Ethanol Extract Modulates the Activity of Antioxidant Enzymes
Ethanol Extract Modulates the Activity of Antioxidant Enzymes
Plant-based preparations with antioxidant and antimicrobial influences can be effectively applied for both the prevention ...
New Schiff Base Clubbed Methylene Derivatives: Design, Synthesis, Biological Screening, Molecular Docking and Pharmacokinetic Studies
New Schiff Base Clubbed Methylene Derivatives: Design, Synthesis, Biological Screening, Molecular Docking and Pharmacokinetic Studies
A novel series of 4,4'-methylene bis(N-substituted benzylidene-2-fluoro aniline) derivatives (SE1 to SE10) was synthes...
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