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Gastric retention for cardiovascular therapy: matching drug properties, dosage-form design, and translational evidence
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Toward sustainable therapeutics: integrating regenerative medicine into pharmacological sustainability frameworks
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Precision targeting in prostate cancer: Mechanistic drivers and the evolving clinical pipeline
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Deubiquitinase inhibitors: from evolving concepts to preclinical evaluation
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Degraders of histone lysine methyltransferases: Progress, challenges, and opportunities
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Pharmacological modulation of ATF6: exploiting a stress-integrative node to overcome drug resistance
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From structural biology to precision medicine—decoding the key receptor in thyroid disorders
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Targeting chemobrain: from experimental models to therapeutic discovery
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Outer membrane as a drug target for the treatment of GNB infections
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Small nucleolar RNAs: Emerging therapeutic and diagnostic frontiers in Alzheimer’s disease
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Covalent small-molecule RNA targeting in Alzheimer’s disease: Computational strategies, challenges and opportunities
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Can agentic AI dent Eroom’s Law? Large reasoning models across the drug discovery and development pipeline
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Universal care under strain: navigating population ageing in Europe
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Interplay between RNA m6A modification and transglutaminase 2 inhibitor effects on mitophagy dysfunction in Alzheimer’s disease
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Single-cell and spatial transcriptomic insights into fibrotic mechanisms and therapeutic opportunities
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Current Clinical Evidence on Nose-to-Brain Drug Delivery
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Reassessing R&D outcomes of leading pharmaceutical companies
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Stop Discovering Peptides: Start Designing Them
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Does Australia’s Reformed R&D Tax Incentive Scheme Spur or Stifle Innovation?
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First Approval of Semaglutide for MASH in India: A Paradigm Shift in MASLD Management?
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Exosomal heterogeneity and functional zonation in cancer drug resistance
The emergence of drug resistance remains one of the most formidable challenges in the effective treatment of solid tumors....
Piezo1 as a therapeutic target in kidney disease: emerging mechanistic insights and translational potential
Prof. Anil Bhanudas Gaikwad is Professor at the Department of Pharmacy, Birla Institute of Technology and Science Pilani (...
Plasmodium falciparum falcilysin as an emerging potential drug target for antimalarial drug discovery
Malaria remains a significant global health challenge, with rising drug resistance highlighting the urgent need for new th...
Advances and challenges in Toll-like receptor-targeted therapy for rheumatoid arthritis
Figure 1 TLR-targeted genetic polymorphisms, mechanism and drug application in three RA pathological manifestations. SNPs ...
Integrating herbgenomics with systems biology approaches for sustainable utilization of medicinal plant resources
Herbal medicines, originating from plants or fungi, have been utilized for over 5000 years and remain a vital and indispen...
Decoding protein kinases in autophagy with small-molecule modulators for cancer therapy
Autophagy is an intracellular degradation and recycling mechanism that preserves cellular homeostasis by breaking down dam...
Circadian disruption in hepatocellular carcinoma: Current findings and future directions of molecular mechanisms
Hepatocellular carcinoma (HCC) is a lethal malignancy with approximately 860 000 new cases and 750 000 deaths annually wor...
PolyBodies for the Treatment of Respiratory Syncytial Virus Infection
Respiratory viruses continue to be a major cause of mortality and pose a significant risk to human health worldwide, espec...
Biotechnology-based therapies for mitigation of pulmonary fibrosis: an update
Pulmonary fibrosis (PF) is a chronic interstitial lung disease that causes inflammation and scarring around the alveoli of...
The role of seaweed-derived natural components in obesity: A systematic review
Advancements in technology have significantly altered people’s lifestyles, leading to extended periods of sitting and redu...
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