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Ethanolic extract of Selaginella tamariscina alleviates DSS-induced ulcerative colitis by restoring epithelial barrier function
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Subacute oral toxicity of Sinopodophyllum hexandrum fruit in mice: Integrated assessment of target-organ injury and gut microbiota alteration
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Pharmacological evaluation of bitter apricot kernels oil: Anti-inflammatory, analgesic, and wound-healing effects
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Surface plasmon resonance-based ligand fishing drives the identification of xanthine oxidase inhibitors from Terminalia chebula for hyperuricemia treatment
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Pharmacodynamic-oriented serum pharmacochemistry-based discovery of the pharmacodynamic material basis and mechanism of Ohwia caudata leaves against acute ulcerative colitis
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Didang Tang downregulates prostatic necroptosis and NETs formation in rats with chronic prostatitis: Evidence from multi-omics analysis and experimental validation
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Fengshi Gutong Capsules alleviate aconitums-induced nephrotoxicity via PXR-mediated efflux of aconitum alkaloid
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Phytochemical analysis and biological activities of Aegle marmelos unripe fruit: An integrated in vitro, in vivo and in silico study
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Chemical characterization by HPLC–ESI–Q–TOF–MS/MS and evaluation of the gastroprotective and antinociceptive activities of the ethanolic extract of Rhynchospora nervosa (Vahl) Boeckeler (Cyperaceae)
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ABCB1 rs2032582 as a potential biomarker for predicting Scutellaria baicalensis Georgi–drug induced liver injury in humans
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Breaking the autophagy–oxidative stress vicious cycle in Alzheimer's disease: Lactiflorin unlocks P62 dual phosphorylation via ULK1 targeting
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Si-Si-Gu-Ben granules alleviate diarrhea-predominant irritable bowel syndrome by modulating gut microbiota and suppressing the TLR4/NF-κB pathway: A combined clinical and animal study
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Potential wound healing effects of Combretum aculeatum Vent. aerial parts; FOXO1/MIP2 modulation supported by LC-QTOF-MS/MS and molecular docking approaches
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Synaptic remodeling and functional recovery: Huan Le Ning decoction mitigates perimenopausal anxiety and depression symptoms via hippocampal reorganization
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Effects of Heidihuang Pill on renal fibrosis and senescence-associated changes in rats with unilateral ureteral obstruction: A fecal metabolomics and Klotho-knockdown study
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Wuwei Huanglian Wan inhibits Helicobacter pylori and alleviates associated gastritis: host metabolic remodeling and altered IL-6/STAT3 signaling
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Shipi Zengye formula simultaneously ameliorates functional constipation and depression by upregulating SLC6A3 and remodeling the Prevotella copri–bile acid axis
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Rehmannioside D directly targets PTP1B to ameliorate metabolic dysfunction-associated fatty liver disease
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Integrative metabolomic and transcriptomic profiling uncovers the therapeutic mechanism of Qi Fu Yin in diabetic encephalopathy
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Daxiefei decoction (Dunhuang Formula) ameliorates acute exacerbation of chronic obstructive pulmonary disease in rats: involvement of the PI3K/AKT/MMP9/TIMP1 signaling pathway
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An integrated metabolome–microbiome analysis revealed distinct regulatory effects of Xiaoer Chiqiao Qingre granules in young versus adult rats with acute upper respiratory tract infection
Xiaoer Chiqiao Qingre Granules (XECQ) is a traditional Chinese medicine (TCM) prescription officially recorded in the Phar...
Danggui Buxue Decoction and its active components alleviate COPD tracheal injury by regulating JAK-STAT pathway and glutathione metabolism in Drosophila and rats
Chronic obstructive pulmonary disease (COPD) continues to be a significant public health concern and an ongoing challenge ...
Safflower washing medicine alleviating acute soft tissue injury via PI3K/Akt pathway
Acute soft tissue injury (ASTI), a common exercise-related condition, significantly impacts health and function. Its core ...
Anticancer mechanisms of Poikilospermum suaveolens root fraction: ethnopharmacological relevance, signaling pathways, and in vitro/in silico studies on MCF-7 cells
Breast cancer is among the most prevalent forms of cancer worldwide, representing a significant cause of morbidity and mor...
Naringin promotes hair regeneration via wnt/β-catenin pathway: A dose-dependent study in C57BL/6J mice
Alopecia, characterized by progressive hair thinning and loss, represents a significant medical and aesthetic concern affe...
OLink proteomic biomarker to predict clinical efficacy of Macaranga sinensis Müll.Arg: A nested case-control study
Volume 361, 24 April 2026, 121243Author links open overlay panel, , , , , Highlights•The clinical application of herbal me...
Levistilide A from Ligusticum chuanxiong alleviates LPS-induced depression- and anxiety-like behaviors by promoting mitophagy through the SIRT3/PINK1/Parkin pathway
Depression is a leading contributor to global mental and physical impairment, and a key component of the global disease bu...
Exploring the effects of Citrus aurantifolia fruits peel essential oil, cultivated in Al-Hasa, in Methotrexate induced kidney and hepatic toxicities: Network Pharmacology, Molecular Docking, and in vivo Experiments
Hasawi lemon, locally termed "Hasawi Lomi," is a regional variety of Citrus aurantiifolia. Cultivated predominantly in the...
Tongmai Yangxin Pill ameliorates doxorubicin-induced cardiotoxicity through m6A/ALKBH5/BNIP3 axis
Doxorubicin (DOX) has been widely used in the treatment of many solid tumors and hematological tumors. However, the widesp...
Mulberry polyphenols (ABRU) promote bone formation and alleviate bone loss via dual regulation of bone metabolism
Bone metabolic homeostasis is essential for maintaining skeletal health. This dynamic balance relies on the finely regulat...
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